Cancer cells need more DNA synthesis but the NADPH/ NADP* ratio is high. Which of the following statement is TRUE? a. Flux through the oxidative reactions is low and the nonoxidative reactions are reversed in order to form ribose 5-phosphate. O b. The oxidative reactions and the isomerase supply both ribose 5-phosphate and NADPH with little flux through the nonoxidative branch. O c. Flux through the oxidative reactions increases and ribose 5-phosphate is shunted into glycolysis by the nonoxidative reactions. d. The ribose 5-phosphate is recycled through the

Cancer cells need more DNA synthesis but the NADPH/ NADP* ratio is high. Which of the following statement is TRUE? a. Flux through the oxidative reactions is low and the nonoxidative reactions are reversed in order to form ribose 5-phosphate. O b. The oxidative reactions and the isomerase supply both ribose 5-phosphate and NADPH with little flux through the nonoxidative branch. O c. Flux through the oxidative reactions increases and ribose 5-phosphate is shunted into glycolysis by the nonoxidative reactions. d. The ribose 5-phosphate is recycled through the

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter20: Electron Transport And Oxidative Phosphorylation

Section: Chapter Questions

Problem 19P

See similar textbooks

Similar questions

pH and in the Chloroplast Proton-Motive Force (Integrates with Chapter 20.) In mitochondria, the membrane potential () contributes relatively more to p (proton-motive force) than does the pH gradient (pH). The reverse is true in chloroplasts. Why do you suppose that the proton-motive force in chloroplasts can depend more on pH than mitochondria can? Why is () less in chloroplasts than in mitochondria?
Which of the following pathways requires molecular oxygen (O2)? a. aerobic respiration b. lactate formation c. alcoholic fermentation d. photosynthesis
A suspension of inside-out submitochondrial particles (i.e., the F1 unit is on the outside of the particle) is placed in a solution that contains ADP, Pi, and NADH. Will increasing the proton concentration of the solution result in ATP synthesis? Explain.
Why are electron carriers (NAD+/NADH and FAD/FADH2) so important in the process of cellular respiration? A)NADH and FADH2 are major components of the ETC, so without them, there would be no ETC in the cell. B)They deliver electrons to the ETC, which in turn sets up chemiosmosis, where most of the ATP is generated. C)They separate the electrons from the protons so that the protons can be moved out of the mitochondrion. D)The electrons that they carry are able to directly phosphorylate ADP in order to generate the bulk of ATP in the cell. E) They transport protons across the mitochondrial membrane. 14.
Energu production pathway is tartgeted bu drugs in melignant cells to control x cancer type. Use your sepculation and tell targeting and destroyin which one energy producing agent of oxydative phosphorylation will be most effective in blocking of the energy production and why?
Where in cellular respiration does feedback inhibition occur? Describe all. (Hint:think about glycolysis, pyruvate processing, and electron transport chain and what's being inhibited in each) What would happen if this feedback inhibition were removed?
NADH dehydrogenase 3 gene codes for a protein in the electron transport chain. Suppose that this protein is exposed to extremely high heat. What is likely to happen to this protein and why? (Be specific as to what will happen and why it will happen. Don't just say it will stop working; explain why.)
What effect will increasing the number of c subunits in ATP synthase have on the P:O ratio? A. It will increase for both NADH and FADH2. B. It will increase for NADH and decrease for FADH2. C. It will decrease for NADH and increase for FADH2. D. It will decrease for both NADH and FADH2. E. It will remain unchanged for both NADH and FADH2.
1)NADH is made from NAD+ by a)An oxidation-reduction reaction b)Oxidative phosphorylation c)A proton gradient d)A dehydration reaction e)Substrate-level phosphorylation 2. The energy used to make ATP via substrate-level phosphorylation is from a(n) a)Electron gradient b)Reduction reaction c)Phosphorylated molecule d)ADP molecule e) Protein gradient 3. Which of the following molecules, as written, is in its reduced form? a)NADH b)O2 c)NAD+ d)FAD e)CO2 4. Cellulose is a good structural molecule because a)The molecule is amphipathic, allow it to interact with water and nonpolar substances b)The bonds between the monomers are difficult to break, increasing its stability c)It is a mix of carbohydrate and protein, allowing it to form multiple types of bonds
You are growing human muscles cells in the lab and you are trying to test how wellthe cells survive with decreasing concentrations of oxygen. As part of yourexperiment, you are measuring the rate of glucose use, the rate of mitochondrial ATPproduction and the pH of the solution surrounding the cells. As the concentration ofoxygen becomes lower änd lower, what changes might you expect to observe inthese cells?A. The rate of glucose use would increase, the rate of mitochondrial ATP productionwould decrease, and the pH of the solution would decrease (become more acidic).B. The rate of glucose use would decrease, the rate of mitochondrial ATP productionwould decrease, and the pH of the solution would increase (become more basic).C. The rate of glucose use would increase, the rate of mitochondrial ATP productionwould increase, and the pH of the solution would decrease (become more acidic)D. The rate if glucose use would decrease, the rate of mitochondrial ATP productionwould decrease, and…
Assuming all the NADH+H+ and FADH2 are used for oxidative phosphorylation, how many net ATP are made from 1 molecule of glucose? (hint: don’t forget to also include substrate level phosphorylation)
ATP levels are high in the liver, NADPH levels are low, but fat biosynthesis needs to happen. What is the function of the pentose phosphate pathway? a. Mode 1 - NADPH and ribose 5-phosphate are being generated b. Mode 2 - ribose 5-phosphate is needed, so only the non-oxidative portion is being used for carbon skeleton rearrangments c. Mode 3 - NADPH is needed, so oxidative portion is operating to make NADPH and non-oxidative portion is operating to regenerate glucose 6-phosphate d. Mode 4 - NADPH and ATP are needed, so oxidative portion makes NADPH, non-oxidative portion does carbon skeleton rearrangements to fuel glycolysis and make ATP