Cell A is actively engaging in growth and division. The cell encounters a damage in its DNA at a certain point in the cell cycle. What would be the reaction in the cells if the damage was sensed Before the R point is passed After passing the R point What would be the similarities and differences in the reaction in the cell in cases a and b? In your answer, briefly include the significance of the R point during the cell cycle

Cell A is actively engaging in growth and division. The cell encounters a damage in its DNA at a certain point in the cell cycle. What would be the reaction in the cells if the damage was sensed Before the R point is passed After passing the R point What would be the similarities and differences in the reaction in the cell in cases a and b? In your answer, briefly include the significance of the R point during the cell cycle

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter10: Cell Division And Mitosis

Section: Chapter Questions

Problem 1ITD: Biologists have long been interested in the effects of radiation on cells. In one experiment,...

See similar textbooks

Similar questions

Biologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.
When studying living cells in a laboratory, researchers sometimesuse drugs as a way to cause cells to remain in a particular phaseof the cell cycle. For example, aphidicolin inhibits DNA synthesisin eukaryotic cells and causes them to remain in the G1 phasebecause they cannot replicate their DNA. In what phase of thecell cycle—G1, S, G2, prophase, metaphase, anaphase, or telophase—would you expect somatic cells to stay if the followingtypes of drug were added?A. A drug that inhibits microtubule formationB. A drug that allows microtubules to form but prevents themfrom shorteningC. A drug that inhibits cytokinesisD. A drug that prevents chromosomal condensation
Beginning with the G1 phase of the cell cycle, describe the levelof compaction of the eukaryotic chromosome. How does thelevel of compaction change as the cell progresses through thecell cycle? Why is it necessary to further compact the chromatinduring mitosis?
When the DNA of a human cell becomes damaged, the p53 geneis activated. What is the general function of the p53 protein?Is it an enzyme, transcription factor, cell-cycle protein, orsomething else? Describe three ways in which the synthesisof the p53 protein affects cellular function. Why is it beneficialfor these three things to happen when a cell’s DNA hasbeen damaged?
When studying living cells in a laboratory, researchers sometimesuse drugs as a way to make cells remain at a particular stage of thecell cycle. For example, aphidicolin is an antibiotic that inhibitsDNA synthesis in eukaryotic cells and causes them to remain inthe G1 phase because they cannot replicate their DNA. In whatphase of the cell cycle—G1, S, G2, prophase, metaphase, anaphase,or telophase—would you expect somatic cells to stay if they weretreated with each of the following types of drug?A. A drug that inhibits microtubule formationB. A drug that allows microtubules to form but prevents them fromshorteningC. A drug that inhibits cytokinesisD. A drug that prevents chromosomal condensation
What is the major difference between M phase and interphase of the cell cycle? We can see activity within the cell only during M phase. Interphase is when the cell divides, whereas M phase is where it is mute. We can see activity within the cell only during interphase. M phase involves color changes, which is why there are chromosomes.
What is the order in which the following events occur during cell division: A. anaphase B. metaphase C. prometaphaseD. telophase E. lunar phaseF. mitosis G. prophaseWhere does cytokinesis fit in?
BPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: Why do you think that very small concentrations of BPA mighthave a large effect on the cell?
Amount of DNA per nucleus over the cell division cycle. At which point in the accompanying figure does MPF reach its highest activity during the cell division cycle? a) I b) II c) III d) IV
A somatic cell has 46 chromosomes aligned at metaphase. How many chromosomes are present at anaphase, immediately after the centromeres have split?
What cellular mechanism(s) ensure that passage through the cell cycle is unidirectional and irreversible? What mo-lecular machinery underlies these mechanism(s)?
Explain why we can say that M-phase of the cell-cycle is triggered by a positive feedback loop. a) What would the consequences be if cohesins were working normally but condensins were not? and b) what stage of the cell cycle would this cause problems in? Why is it important for the centrosome to duplicate during G1-G2 (interphase) before M phase? The kinetochores serve as a link between the sister chromatids and the microtubules attached to the mitotic spindle. a) How are microtubules still able to exhibit dynamic instability after they are bound to the sister chromatids and b) why is this important to mitosis? As the name suggests, the Anaphase-promoting-complex (APC), promotes the 4th phase of mitosis by separating the sister chromatids so they can travel to separate poles of the cell, and prevents them from being re-zipped together. Describe how APC does these two things (Hint: one involves M-cyclin and the other involves…