
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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What cellular mechanism(s) ensure that passage through
the cell cycle is unidirectional and irreversible? What mo-
lecular machinery underlies these mechanism(s)?
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- By what molecular pathway does loss of cell cycle regulation in an organism lead to cancer? What genetic changes can cooperate to accomplish the cancer cell’s escape from the normal balance of cell growth?arrow_forwardHow does p53 induce apoptosis? How does the cell determine what "too much" damage is? Meaning, how can it tell if the damage to the DNA is too severe to fix in order for the cell to move on to S phase? Thank you.arrow_forwardBPA is a chemical compound that has historically been used in themanufacture of plastic products. However, cells often mistake BPAcompounds for hormones that accelerate the cell cycle. Because ofthis, BPA is associated with an increased risk of certain cancers. Question: Why do you think that very small concentrations of BPA mighthave a large effect on the cell?arrow_forward
- Artificially induced apoptosis (controlled cellular death) is found to be an effective treat- ment for some forms of cancer. Which of the following describes the most likely mechanism by which apoptosis might be induced? A B с D by causing ribosomes to increase the rate of protein synthesis by triggering the division of mitochondria in the cell to increase ATP production by increasing the expression of membrane-bound glucose protein channels by causing lysosomes to release digestive enzymes into the cytosolarrow_forwardIn a dividing cell, the duplicated sets of chromosomes move along microtubules to opposite ends of the cell. How would you use an inhibitor to show that microtubules are essential for chromosome separation? What control treatment(s) would you use? What kind of cell junctions would you expect to find, and why, in a small animal where a chemical signal passes rapidly through cells to go from the head to the tail?arrow_forwardWhat celluar events/processes are associated with G1,S,G2,and M phases of the cell cycle? With the phases of mitosis? Some example: A. DNA replication B. Beginning of mitosis C. Normal cell growth and function D. Breaksdown of nuclear membrane E.Separation of sister chromatids F.Alignment of chromosomes on the equator of the cell H.Triggering the compaction and condensation of chromosomes I. Attachment of microtubles to kinetochoresarrow_forward
- Explain Cyclin-dependent kinases (CDKs) control the cell cycle by phosphorylating other proteins?arrow_forwardCancer, the uncontrolled growth of cells, often results in a tumor, or mass of abnormal cells. Some cancerous tumors consist of many cells that are much smaller than normal. According to Figure 1, what part of the cell cycle is most likely being affected? Explain.arrow_forward
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