Cetrizine is chiral. Like many chiral drugs, one enantiomer of cetrizine is more active than the other enantiomer or the racemic mixture. The levorotatory (S) enantiomer of cetrizine is more active, and syntheses have been developed that produce only the desired enantiomer in high yield. Label the chiral center of cetrizine with an asterisk. CI Cetrizine -CO,H

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter16: Aldehydes And Ketones
Section: Chapter Questions
Problem 16.78P
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Cetrizine is a nonsedating antihistamine. The first step in a synthesis of cetrizine involves the following Grignard reaction

Cetrizine is chiral. Like many chiral drugs, one enantiomer of cetrizine is more
active than the other enantiomer or the racemic mixture. The levorotatory
(S) enantiomer of cetrizine is more active, and syntheses have been developed
that produce only the desired enantiomer in high yield. Label the chiral center of
cetrizine with an asterisk.
CI
Cetrizine
-CO,H
Transcribed Image Text:Cetrizine is chiral. Like many chiral drugs, one enantiomer of cetrizine is more active than the other enantiomer or the racemic mixture. The levorotatory (S) enantiomer of cetrizine is more active, and syntheses have been developed that produce only the desired enantiomer in high yield. Label the chiral center of cetrizine with an asterisk. CI Cetrizine -CO,H
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