Free Energy Free Energy Free Energy Free Energy CHEMISTRY 2400 EXPERIMENT 7: BROMINATION OF CINNAMIC ACID WINTER 2022 Progress of the reaction Progress of the reaction Progress of the reaction Progress of the reaction Page 19 of 19 2. The bromination of 2-butene is an exergonic reaction. Br H3C. Br2 CH3 CH3 Br a. Draw the mechanism for the reaction (you may ignore the stereochemistry for this question). b. In the mechanism drawn above, identify any intermediates. C. How many transition states are involved in the above mechanism? Without drawing the transition state(s), indicate where they occur in the mechanism. d. Which of the following reaction co-ordinate diagrams best illustrates this reaction? Explain briefly. On the diagram, draw the structures of the reactants, products and intermediates at the correct locations on the diagram and indicate which position(s) correspond to the transition state(s). Page 18 of 19 EYRERIMENT 7: BROMINATION OF CINNAMIC ACID WINTER 2022
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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