Pralidoxime is an antidote to organophosphate poisoning. Which of the following is false? N-OH O It breaks P-O bond in the phosphorylated serine. O It is designed to replace hydroxylamine because it is less toxic and more effective. O The design of pralidoxime took advantage of the vacancy of anionic binding region of inhibited acetylcholinesterase. O The methylated pyridine serves as nucleophile and react with the phosphate ester.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter25: Biomolecules: Carbohydrates
Section25.SE: Something Extra
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Pralidoxime is an antidote to organophosphate poisoning. Which of the following is
false?
N-OH
O It breaks P-O bond in the phosphorylated serine.
O It is designed to replace hydroxylamine because it is less toxic and more effective.
O The design of pralidoxime took advantage of the vacancy of anionic binding region of inhibited
acetylcholinesterase.
O The methylated pyridine serves as nucleophile and react with the phosphate ester.
Transcribed Image Text:Pralidoxime is an antidote to organophosphate poisoning. Which of the following is false? N-OH O It breaks P-O bond in the phosphorylated serine. O It is designed to replace hydroxylamine because it is less toxic and more effective. O The design of pralidoxime took advantage of the vacancy of anionic binding region of inhibited acetylcholinesterase. O The methylated pyridine serves as nucleophile and react with the phosphate ester.
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