Cleavage of a phosphate bond is needed for de-polymerization of which mature polymer? Neither microfilaments nor intermediate filaments Microfilaments only Both microfilaments and intermediate filaments Intermediate filaments only
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- If a cell's lysosomes burst, the cell would ______. digest itself divide into two cells shrivel need to manufacture more lysosomesWhich of the following describes an F-actin microfilament? A flexible, helical filament composed of two strands assembled from G-actin 13 protofilaments composed of heterodimers with a hollow core a flexible filament composed of 13 interwoven protofilaments Eight tetramers twisted into a rope-like filamentWhich of the following are differences between the assembly processes of intermediate filaments versus that of actin microfilaments? A. New subunits are added internally to the intermediate filament rather than at the ends B. Assembly requires GTP rather than ATP C. Intermediate filaments are assembled from multiple tetramers rather than from monomers. D. A and B E. A and C
- You’re having a discussion with a colleague who insists that intermediate filaments, IFs, provide very little mechanical strength to cells. How can you rebut this and provide quantitative, experimental evidence to measure the strength of an intermediate filament using microscopy?In nonmuscle cell locomotion, which protein is activated to nucleate a filament? Arp2/3 Vinculin Gelsolin Profilin CofilinWhen combining 1ml of lysosome solution with a concentration of 5mg/ml and 1ml of water what is the final concentration of the lysosome solution after adding 8.0 of a biuret reagent to the solution 2.5mg/ml 1mg/ml 0.5mg/ml 5 mg/ml
- Why is it that intermediate filaments have iden-tical ends and lack polarity, whereas actin filaments andmicrotubules have two distinct ends with a defined polar-ity?Which of the following is reponsible for the synthesis of proteinsthat are being exported from the cell?a. smooth ERb. rough ERc. lysosomed. peroxisomePlease help me with this question. More than one answer may be correct. Intermediate filaments Options: A) are larger than 10nm in diameter B) have a hollow core C) include microtubules D) uses a filamentous monomers E) have multiple types of monomers they can be composed of.
- Actin and microtubules have polarity, intermediate filaments have no polarity. What is the main consequence of this difference?Proteoglycan aggregates in tissues form hydrated, viscousgels. Can you think of any obvious mechanical reason whytheir capacity to form gels is important to cell function?[Hint: Liquid water is virtually incompressible.]Neurofilament proteins assemble into long, intermediate filaments , found in abundance running along the length of nerve cell axons. The C-terminal region of these proteins is an unstructured polypeptide, hundreds of amino acids long and heavily modified by the addition of phosphate groups. The term “polymer brush” has been applied to this part of the neurofilament. can you suggest why?