Compare toxigenic E. coli disease with invasive disease. How are they different?
Introduction:
There are various clinical subtypes of diarrhoeal diseases. The condition in which there is the passage of three or more loose or liquid stools in a day than usual is referred to as diarrhea. It may be due to some microbial infection or may occur as a consequence of other gastrointestinal ailments like coeliac disease or inflammatory bowel disease. On the other hand, dysentery is diarrhea with excessive mucus and blood mostly associated with fever, tenesmus, and abdominal pain.
Answer:
The toxigenic E.coli disease and invasive E.coli disease are both caused by organisms that belong to Diarreagenic E.coli. Diarrheagenic E.coli are different from the commensal E.coli that reside in the intestinal tract. Only a few serotypes of E.coli expressing the enterotoxin or other mechanisms of virulence can cause diarrhea. The six types of diarrheagenic E.coli are as follows:
- Enteropathogenic E.coli (EPEC)
- Enteroinvasive E.coli (EIEC)
- Enteroaggregative E.coli (EAEC)
- Enterotoxigenic E.coli (ETEC)
- Enterohemorrhaic E.coli (EHEC)
- Diffusely adherent E.coli (DAEC)
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