Consider the following amino acid sequence :a)Where might bends or βturns occur? b)Where might intrachain disulphide cross-linkages be formed? c)Assuming that this sequence is part of a bigger globular protein, indicate the probable location (on the surface or interior of the protein) of the following amino acid residues: Asp, Ile, Thr, Ala, Gln and Lys. Explain your reasoning

Essentials of Pharmacology for Health Professions
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Chapter5: Abbreviations And Systems Of Measurement
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Our understanding of how proteins fold allows us to make predictions about protein structure based on primary amino acid sequence data. Consider the following amino acid sequence

:a)Where might bends or βturns occur?

b)Where might intrachain disulphide cross-linkages be formed?

c)Assuming that this sequence is part of a bigger globular protein, indicate the probable location (on the surface or interior of the protein) of the following amino acid residues: Asp, Ile, Thr, Ala, Gln and Lys. Explain your reasoning

Пе-Ala-His -Thr - Тyr-Gly-Pro- Phe -Glu-Ala-Ala- Met-Сys -Lys-
1
2
3 4 5
6 7
8.
9.
10
11
12
13
14
Trp-Glu-Ala – Gln-Pro-Asp-Gly-Met-Glu-Cys-Ala-Phe–His-Arg
15
16
17
18
19
20
21
22
23
24
25
26
27
28
Transcribed Image Text:Пе-Ala-His -Thr - Тyr-Gly-Pro- Phe -Glu-Ala-Ala- Met-Сys -Lys- 1 2 3 4 5 6 7 8. 9. 10 11 12 13 14 Trp-Glu-Ala – Gln-Pro-Asp-Gly-Met-Glu-Cys-Ala-Phe–His-Arg 15 16 17 18 19 20 21 22 23 24 25 26 27 28
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