Consider this scheme. Why does a ring form with a single ethylene glycol on A rather than two molecules of ethylene glycol to form acyclic acetals? Intramolecular reactions are A unfavorable when compared to intermolecular reactions Acyclic molecules are unfavorable compared to rings В in all cases The change in entropy is favorable for ring formation C and strain is low in a five- membered ring Sterics prevents acyclic molecules from forming in this D

Organic Chemistry
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Author:John E. McMurry
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Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution
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Consider this scheme. Why does a ring
form with a single ethylene glycol on A
rather than two molecules of ethylene
glycol to form acyclic acetals?
Intramolecular reactions are
A
unfavorable when compared to
intermolecular reactions
Acyclic molecules are
unfavorable compared to rings
В
in all cases
The change in entropy is
favorable for ring formation
and strain is low in a five-
membered ring
Sterics prevents acyclic
molecules from forming in this
D
case
H
HCI
+ HOCH2CH2OH
H + H2O
Transcribed Image Text:Consider this scheme. Why does a ring form with a single ethylene glycol on A rather than two molecules of ethylene glycol to form acyclic acetals? Intramolecular reactions are A unfavorable when compared to intermolecular reactions Acyclic molecules are unfavorable compared to rings В in all cases The change in entropy is favorable for ring formation and strain is low in a five- membered ring Sterics prevents acyclic molecules from forming in this D case H HCI + HOCH2CH2OH H + H2O
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