CYTOSOL (Oロ EXTRACELLULAR SPACE A 1. M6P receplor bound to ligand 2.0 prolein with an (N-SIG] only in a class E yeast mutant 3 plasma membrane v-SNARE 4 clathvin
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- 6. "Coated pits" are formed as a result of a. clathrin triskelions polymerizing of the surface of secretory vesicles b. clustering of v-SNAREs on the surface of the plasma membrane c. endocytosis of ER resident proteins carrying the KDEL sequence d. clustering of cell surface receptors bound to their ligands e. acidification of late endosomes.List the type, location (ex. C-terminus), and key feature (stretch of certain type of amino acids) for the sorting signal sequences you predict be present on GFP construct that allows it to end up in the organelle specified. If none, please note: a. GFP as a soluble lysosomal resident b. GFP ends up in the chloroplast stroma c. GFP ends up in the nucleus d. GFP is localized to the plasma membrane, with 3 transmembrane domains, and its N-terminus in the cytosolWhat would most likely occur to nuclear-cytoplasmic shuttling if the intrinsic GTPase activity of RAN was slowed down by 50%? Group of answer choices RAN would not bind exportin and proteins would accumulate in the nucleus All of the answers are likely None of the answers are likely Importin beta would not release from RAN in the cytoplasm and nuclear import would slow down RAN would not bind to importin beta and protein cargo in the nucleus would not release
- FtsZ proteins direct the formation of a ___________ that will eventually form the new cell walls of the daughter cells. contractile ring cell plate cytoskeletom septum26.With regard to cell signalling, which of the following do not represent exogenous signals? A. Neurotransmitters B. Invading microorganisms C. Light D. Odours E. All of the above statements are correct 27.Which of the following statements correctly describe distinct aspects of microtubule dynamic instability? A. αβ-tubulin dimers must contain GTP bound to both subunits to be added to a microtubule B. Terminal β-subunits have essentially negligible rates of GTP hydrolysis C. The addition of a new αβ-tubulin dimer to a growing microtubule results in GTP hydrolysis within the formerly terminal β-tubulin subunit D. The end of each microtubule has a cap of GTP-bound β-subunits, with the central region of the microtubule primarily consisting of GDP-bound β-subunits E. All of the above statements are true 28.All of the following statements regarding myosin are true, with the exception of: A. Myosin is a multimeric protein made up of heavy and light chains B.…Capacity to carry oxygen by sickle cell hemoglobin is reduced due to A premature termination of a- globin chain translation b splice junction mutation c formation of a rope-like polymer of deoxyhemoglobin d Micro RNA expression in hematopoietic celles E replacement of O2 in heme by cyanide ion
- Which of the following statements is true? Question 9 options: a) Executioner caspases are activated by cleavage. b) Initiator caspases are activated by cleavage. c) Executioner caspases are activated by dimerization. d) Executioner caspases trigger apoptosis but initiator caspases does not.What is the role of the Ran-GAP protein in nuclear transport? Ran-GAP converts RanGTP to RanGDP Ran-GAP is a receptor on the nuclear membrane Ran-GAP is not directly involved in nuclear transport, it is a transcription factor Ran-GAP shuttles between mitochondria and the nucleus Ran-GAP converts RanGDP to RanGTPUnfolded proteins in the lumen of the endoplasmic reticulum are directly detected by which protein? Bip IRE-1 ribosome COPII
- Fill in the blank sentences below: ________ is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm; inside the nucleus , ________________ process happens which involve making an RNA copy of a gene sequence known as ____ molecule, that leaves the cell nucleus through the ______ and enters the cytoplasm where it binds to a ________ that serves as a template for ______ that directs the synthesis of the protein, which it encodes; ribosomes are of two kinds, one is floating in the cytoplasm which is the ______ribosome while the other is attach to ER known as ___ ribosome; proteins in the cell can be packaged, modify and distribute by the __________ and can be delivered to an organelle that produce ATP which is the _____.What is the role of the Ran-GEF protein in nuclear transport? Ran-GEF converts RanGTP to RanGDP Ran-GEF binds Ran-GAP on inside of nucleus to speed up transport Ran-GEF converts RanGDP to RanGTP Ran-GEF maintains the RanGTP concentration on the inside of the nucleus low Ran-GEF binds directly to the nuclear pore to facilitate transportSelect all of the statements that apply to transcytosis. A. Transfers dimeric IgG B. Transfers dimeric IgA C. Utilizes the poly-Ig receptor D. Utilizes the Brambell receptor E. Two receptors must bind to move the Ab F. Protease is used to release the Ab after it has moved G. Change in pH is used to release the Ab after it has moved H. Transfers monomeric IgA