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Describe kinases and cyclins. How do they interact to cause cells to move through the cell cycle?
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- List the functions of kinases and cyclins, and describe how they interact to cause cells to move through the cell cycle.Explain how cyclin and cyclin-dependent kinases control the cell cycle.Describe how cyclins and cyclin-dependent kinases are related. How do these molecules help regulate the cell cycle?
- Which of the following is the primary method by which cyclin proteins are regulated to influence entry into the cell cycle or transition from one stage to the next? A. Transcriptional upregulation and translation followed by targeted ubiquitin-mediated degradation by a proteasome. B. Phosphorylation to regulate the activity of the kinase site. C. An activating phosphorylation and an inactivating phosphorylation. D. All of these are mechanisms that can be used to regulate cyclins.Describe the molecules that control the cell cycle through positive and negative regulation.Explain the action of cyclin-dependent kinases inregulation of the cell cycle.