Describe the importance of ubiquitin-dependent degradation of soluble proteins.

Q: Describe results that could be obtained from ribosomeprofiling that would indicate the existence of…

A: Ribosome profiling is a technique which is based on deep sequencing of ribosome protected fragments…

Q: Explain the steps associated with translocation of ER proteins across the ER membrane.

A: The Endoplasmic reticulum(ER) plays an important role and it would be the place where the membranes…

Q: Explain why in cells that are genetically NF1–/–, basal levels of GTP-bound activated Ras are higher…

A: Neurofibromatosis type 1 (NF1) is a typical hereditary problem portrayed by various neurofibromas,…

Q: Define the term alpha–gamma coactivation? What is its role?

A: In physiology, Alpha-gamma coactivation is the process in which muscle maintains the length during…

Q: Define SCF-proteasomedegrades phosphorylatedS phase CDK inhibitor

A: Misregulation of any aspect of the cell cycle may lead to developmental defects and diseases such as…

Q: Identify the two general functions of the proteins encoded bytumor-suppressor genes.

A: Gene is the unit of heredity that is transferred from a parent to offsprings. Proto-oncogenes are…

Q: Inactive precursor proteins with removable signal peptides are called _____________.

A: A protein precursor is an inactive protein that can be turned into an active form by…

Q: What is the best inhibitor of endoplasmic reticulum stress in human ?

A: Endoplasmic stress occurs when the capacity of the ER to fold proteins becomes saturated. There are…

Q: Describe the similarities and differences in the structures of GPCRs specific for various ligands…

A: A very large group of proteins that detect the substances outside the cell and generate various…

Q: Determine whether a protein can act the same way in two different types of cells and whether it is…

A: A mutation is a change in the genome's or DNA's sequence. Evolutionary processes frequently involve…

Q: Activation of the CAP protein, inactivation of the Lac Repressor, activation of the TRP Repressor,…

A: Answer  Option A - Allosteric modifications

Q: Explain how mutant porins could help to make Beta-lactamases more effective. Could mutant porins…

A: Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to β-lactam…

Q: Describe the causes of proteolytic stress in a living cell.

A: Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the…

Q: Explain the functions of Ubiquitin and Ubiquitin-Related Molecules.

A: Introduction  Proteins are the essential biomolecules which plays a diverse role. Almost all…

Q: Explain how catabolite repression depends on an activatorprotein

A: Introduction  All the gene expressions are under high regulation and this is necessary to avoid over…

Q: Describe the function and significance of ubiquitin and the proteasome in the regulation of gene…

A: Ubiquitin is a protein that marks the proteins which have completed their lifespan and then…

Q: Explain the relationship between the variable number of tandem repeats in the insulin promoter…

A: Autoimmune diabetes is also called type 1 diabetes mellitus. This type of diabetes mellitus is…

Q: riefly Describe What are the differences between selective and non-selective beta blocker? Describe…

A: The extent to which a particular medication can act on a certain site compared to other sites of the…

Q: Define Ubiquitin-Mediated Protein Degradation ?

A: Introduction  Proteins are the essential biomolecules which plays a diverse role. Almost all…

Q: Some transcription factors contain bromodomains. Explain the function of the bromodomain?

A: Transcription factors are responsible for intiating the transcription process. The transcript…

Q: Explain the importance of the proper targeting of nascent polypeptides

A: Protein targeting is the biological process by which proteins are transported to their destinations.…

Q: What is denaturation? Give examples. What are the factors that affects the proteir synthesis?

A: Proteins are defined as an unbranched polymers which are made up of 22 amino acids. They are usually…

Q: Describe the relationship between AMPK and mTORC1

A: AMPK is an activated protein kinase enzyme present in the cells, and it gets activated in the…

Q: How is ATCase regulated to generate precisely the amount of pyrimidines needed by the cell?

A: Aspartate transcarbamoylase (ATCase) catalyzes the first step of pyrimidine synthesis. It converts…

Q: distinguish between IS and Tn transposableelements

A: The gene in prokaryotes and eukaryotes that are capable of moving from one position to another…

Q: What effect does binding of the IRF protein to the IRE in the mRNA encoding ferritin have on the…

A: Iron regulatory proteins(IRP) are previously known as IRF or IRE-BP. They plays a major role in iron…

Q: Rare gain-of-function mutations cause increased _______________production, synthesis of an altered…

A: Mutation is the change in an organism’s DNA sequence. The change may occur in the sequence of bases…

Q: Describe the steps that need to occur for the glucocorticoid receptor to bind to a GRE.

A: Glucocorticoids can be defined as the are hormones that are essential for life and their synthesis…

Q: (c) Draw the absolute configuration of Cholesterol. How Progesterone can be synthesized from…

A: Basic nucleus of cholesterol is formed by a sterol nucleus. This sterol nucleus is made of four…

Q: Explain how can cAMP’s activation of a single molecule, cAMPdependent protein kinase, be common to…

A: Receptors are proteins which bind with ligand molecules and trigger a signaling pathway. Ligands are…

Q: Define quorum sensing and provide examples of cellular processes regulated by quorum sensing

A: Bioluminescence is the process of generation and emission of light(chemiluminescence) by a living…

Q: Discuss Covid-19

A:

Q: Does adenylate cyclase become more active when the inhibitory (Gia) protein is mutated and increases…

A: The GPCR pathway involves activation of cell surface receptor that is a 7 pass transmembrane…

Q: summarize the role of galactose, GAL80, GAL4, GAL3 in relation to upstream activator sequence

A: An upstream activating sequence:It is also known as upstream activation sequence or UAS. It is a…

Q: How can cAMP’s activation of a single molecule?

A: Introduction  cAMP (Cyclic Adenosine Monophosphate) is a secondary messenger which gets produced in…

Q: List three examples of steroid transport proteins.

A: Introduction: Steroid hormones are lipid-soluble. Therefore they are bound to certain proteins for…

Q: Explain fully the ubiquitin proteosome system

A: Proteosome is the protein complex that can degrade unwanted or damaged proteins by the process of…

Q: Signal transduction pathway. Sketch a G protein in the active and inactive stages, and label its…

A: Signal transduction can be defined as the process by which physical/chemical signals are transmitted…

Q: What type of regulation does the interaction of BPG with hemoglobin represent?

A: 2, 3-Bisphosphoglycerate (2,3-BPG) is most abundant organic phosphate in the red blood cell. Molar…

Q: Describe the role of pH in regulating the interaction between mannose 6-phosphate and the M6P…

A: The term pH stands for hydrogen potential. It is been stated that they are defined to decide whether…

Q: What role does ubiquitin play in the degradation of proteins?

A: Proteins are macromolecules that exhibit varied functions in the cells. All enzymes are proteins and…

Proteins

We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.  

Protein Expression

The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.