Describe the most common molecular mechanism for recessively inherited human genetic diseases such as cystic fibrosis

Q: Explain various types of single gene disorders observed in humans

A: Genetic disorders need to study to find out treatment solutions. Single gene disorders are one of…

Q: Explain the term maternal inheritance? Which characters show this type of inheritance?

A: Genetics is the study of heredity in general and genes in particular. Genetic research is one of…

Q: What is meant by the term genetic variation? Give two examplesof genetic variation . What…

A: Genetics is a study of genes, heredity, and genetic variation in an organism. Living organisms…

Q: Explain how it is possible for a person with a translocationor an inversion to be phenotypically…

A: Chromosomes are the condensed packaged structure of the genetic material of an organism. The…

Q: Explain the two major mechanisms by whichchromosomal rearrangements take place.

A: The breaking and reassembling of chromosomal segments accompanying evolution that can occur within…

Q: Describe some of the key features of cytoplasmic inheritance. Why do traits that are inherited in…

A: Answer :  Key features of cytoplasmic inheritance :   Cytoplasmic inheritance from mother side…

Q: Explain about the pleiotropic gene.

A: A gene is a stretch of nucleotides present in the DNA. It codes for the synthesis of an RNA or…

Q: In ___________ heterogeneity, a variety of mutations in a singlegene cause disease. Compound…

A: The genetic heterogeneity occurs through the production of single or similar phenotypes through…

Q: Define the term epigenetic inheritance, and describe twoexamples

A: Epigenetics is basically a study of heritable changes in gene expression that does not involve the…

Q: Describe the molecular mechanisms that account for differenttypes of inheritance patterns involving…

A: An inheritance pattern that obeys the law of segregation and the law of independent assortment in…

Q: describe some of the human genetic disorders that are caused by nondisjunction?

A: Step 1 Nondisjunction is the non separation of homologous chromosomes during anaphase I that brings…

Q: what is the probability that he might be a carrier of the recessive gene?

A: Cystic fibrosis is associated with the CFTR gene that encodes a protein that helps thin the mucous…

Q: In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) gene…

A: Recessive gene traits are the ones which are expressed only when two copies of the recessive genes…

Q: Ehler-Danlos syndrome is a rare disorder caused by a mutation ina gene that encodes a protein called…

A: The Ehler-Danlossyndrome is a disorder caused by a mutation in the gene codes for the protein…

Q: Explain the following term: Allele:

A: DNA is the genetic material present in most of the living organisms. The DNA is made up of 4…

Q: Describe the features of genes with five (5) statements

A: The term gene was coined by Wilhelm johannsen who banish botanist.Gene is word come from the Greek…

Q: Club foot is one of the most common congenital skeletal abnormalities, with a worldwide incidence of…

A: Given data: Club foot is autosomal dominant trait with incomplete penetrance. It’s caused by PITXI…

Q: Explain the functional relationship and their roles in inheritance of DNA, genes, alleles, and…

A: Deoxyribonucleic acid or DNA is a molecule composed of two polynucleotide chains that coil around…

Q: Lesch-Nyhan syndrome is due to a mutation in a gene that encodesa protein called…

A: Pedigree or family tree is a representation of an individual in a family or close relatives that…

Q: Explain the difference between maternal inheritance of organelle DNAs and maternal effect…

A: Branch of biology that deals with the concepts of inheritance and variation is called genetics. It…

Q: Relate the basic principles of genetics to the inheritance of human traits.

A: DNA(deoxyribonucleic acid) is a double-stranded helical genetic material found in the nucleus of…

Q: List some common genetic disorders, state the symptoms of each, and describe the inheritance pattern…

A: Genetic disorders are diseases caused due to mutations in specific genes. These mutated genes are…

Q: What is extranuclear inheritance? Describe three examples

A: DNA is the genetic material found in all prokaryotic and eukaryotic cells. DNA is double stranded…

Q: Describe how a biparental pattern of extranuclear inheritance couldresemble a Mendelian pattern of…

A: The Mendelian inheritance and the extranuclear inheritance has major contrast as the genetic…

Q: Tay-Sachs disease is caused by loss of function mutation in a gene on chromosome 15 that codes for…

A: Tay-Sachs disease is a rare inherited disorder and this is due to mutation occurring in HEX A gene…

Q: A study of three generations in a family of a male colleague of the authors indicated that many of…

A: Cardiovascular diseases are a group of disorders of the heart and the blood vessels. They include:…

Q: Categorize each of the following events as an example of genetic inheritance or epigenetic…

A: * genetic inheritance Inheritance is the process in which genetic information is passed on from…

Q: Explain with reason the features of the human pedigree which indicate that a mutation at…

A: The heart of the cell's power is its mitochondria. It has mtDNA, or mitochondrial DNA, which is its…

Q: Suppose genetic analysis reveals a serious mutation in a gene in the green region of the left-hand…

A: Chromosomes are filamentous bodies present in the nucleus. They have the ability of self-replication…

Q: Give the F1 genotypes of  GgXHXh    and      GgXhY

A: Genotype is the representation of genetic constitution in the form of allelic combinations.…

Q: Describe the exact DNA mutation that has occured, to create the mutant dystrophin allele.

A: Complex of dystrophin and glycoprotein (DGC). Dystrophin is a rod-shaped protein that binds the…

Q: Cystic fibrosis in humans is caused by mutations in a single gene and is inherited as an autosomal…

A: Cystic fibrosis is caused due to mutation in gene that codes for the protein Cystic fibrosis…

Q: Explain, at the molecular level, why human genetic diseases oftenfollow a simple Mendelian pattern…

A: Genes are the set of nucleotides present in a chromosome that encodes for particular information…

Q: List two types of multifactorial inheritances and explain them.

A:

Q: a. On the basis of this pedigree, what is the most likely mode of inheritance for the disease?…

A: Dent disease is a rare genetic disorder related to the kidney. This disease is characterized by the…

Q: List the three basic categories of chromosome mutations and define each one.

A: Aneuploidy refers to a condition of an abnormal or unusual number of chromosomes. Normally each…

Q: How to determine the mode of inheritance of phenotypes in humans ?

A: INHERITANCE IN HUMANS:-  It includes several types of inheritances:- 1) Autosomal dominance 2)…

Q: Give bilological term for an alternation in the genetic material that can be inherited.

A: Step 1 Genetic alteration includes chromosomal abnormalities and gene mutations. It occurs due to a…

Q: explain Non-Mendelian Inheritance of Mitochondriaand Chloroplasts

A: Mendelian inheritance is applicable only in case of sexual reproduction. In case of asexual…

Q: What are some general conclusions from human genomic studies regarding the number of genes present…

A: Genes are the units of heredity that are transmitted through generations. Genes contain the genetic…

Q: In a particular strain of Neurospora, a poky mutation exhibits biparental inheritance, whereas poky…

A: The pattern of inheritance of genes relates to the reproduction of organisms. Most of the characters…

Q: Indicate and explain at least three examples of abnormalities in genes and chromosomes

A: Three of the various abnormalities associated with genes and chromosomes encompass Schizophrenia,…

Q: Define about Tay–Sachs Disease:The Molecular Basis of a Recessive Disorder in Humans ?

A: To produce disease, both genes in a pair must be faulty. Carriers are people who have only one…

Q: Explain the term pleiotropy.

A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…

Q: Compare and contrast the molecular mechanisms leading to FX syndrome and to FSHMD.

A: Introduction :- A gene originally known as FMR1 gene by scientists and responsible for FXS is…

Q: Briefly describe what is a meaning of genetic variation.

A: Variation are distinctive changes that takes place in individuals or set / group of individuals . It…

Q: identify two main themes underlying the phenomena of chromosomal changes?

A: Chromosome is a compact structure of a DNA molecule wrapped around some proteins. It is generally…

Q: Explain why loss-of-function alleles often follow a recessivepattern of inheritance.

A: This is observed that a wild type allele is enough to produce the wild type phenotype often as a…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.