Determine Km, Vmax, and kcat (in 1/s) for VF-6-2 efflux out of vesicles made from DV membranes with wild type PfCRT. What does the mutation in PfCRT appear to do to transport of VF-6?
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Determine Km, Vmax, and kcat (in 1/s) for VF-6-2 efflux out of vesicles made from DV membranes with wild type PfCRT. What does the mutation in PfCRT appear to do to transport of VF-6?
![Wild type PFCRT activity
1.2
1
0.8
y = 10.64x + 0.0569
R2 = 0.9977
0.6
0.4
0.2
0.02
0.04
0.06
0.08
0.1
0.12
1/[VF-6] (1/uM)
1/VF-6 efflux (h/pmol)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Facf7f7d4-0a2e-4492-8754-e1a4249f75ff%2F733cbf02-4a71-4083-bc7d-3f13cf9c2160%2Fvlp9val_processed.png&w=3840&q=75)
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