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Asked Dec 26, 2019
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Devise a synthesis of CH3CH2CH2CHO from two-carbon starting materials.

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Expert Answer

Step 1

The synthesis of CH3CH2CH2CHO from 2 C starting material is shown as below,

The 2 C starting material used is acetylene.

First, acetylide anion is formed using strong base NaH, and then nucloephilic alkyl chloride attacks the anion.

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