Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions showing the conversion of hypoxanthine to dATP and dGTP.
Q: . Most bacterial mutants that require isoleucine for growth also require valine. Why? Which enzyme…
A: A mutation is a permanent alteration in the sequence of nitrogenous bases of a DNA molecule.
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Q: Sodium nitrite, a common food preservative (page 906), is capable of causing mutations in an acidic…
A: Sodium nitrite, a common food preservative , is capable of causing mutations in an acidic…
Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…
A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…
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A: Methionine is an amino acid which is found in meat, fish and dairy products and it plays an…
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Q: In pyrimidine nucleosides, the anti conformation predominates. Explain. Do the purine nucleosides…
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Q: Most bacterial mutants that require isoleucine for growth also require valine.Why? Which enzyme or…
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Q: What fragments can be generated in the decapeptide Gly-Lys-Ala-Met-Gly-Gly-Phe-Tyr-Trp-Ala if is…
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Q: By means of a structural formula, show how S-adenosylmethionine is a carrier of methyl groups.
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Q: What complication could arise from the biological synthesis of ceramide?
A: * ceramides composed of sphingosine and fatty acid. * They are mainly present in cell membranes with…
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- What would be the effect on the activity of phosphofructokinase of the mutation of Asp103 to the unusual amino acid shown below? Explain in terms of actual structures of the side chains of Asp and this unusual amino acid.α-D-galactose from β-D-glucose can be differentiated using which method of analysis? A. Methylation analysis B. All of these C. NMR by the change in chemical shift D. Use of exoglycosidasesIn a-c below, will the residue on the right-hand side increase or decrease the pKa of the residue on the left-hand side? Explain.
- Describe the chemical difference between mannose and heptyl alpha-D-mannose. Why does FimH have a higher affinity for heptyl a-D-mannose versus methyl a-D-mannose?When the amino acid sequences of insulin isolated from differentorganisms were determined, some differences were noted.For example, alanine was substituted for threonine, serine wassubstituted for glycine, and valine was substituted for isoleucineat corresponding positions in the protein. List the single-basechanges that could occur in triplets to produce these amino acidchanges.What does the high-energy molecules adenosine triphosphate fforms and reduced forms of nicotinamide adenine dinucleotide means?
- . In Figure 6-11,a. in view of the position of HPA oxidase earlier in thepathway compared to that of HA oxidase, would youexpect people with tyrosinosis to show symptoms ofalkaptonuria?b. if a double mutant could be found, would you expecttyrosinosis to be epistatic to alkaptonuria?Why is there no net gain of methionine if homocysteine isconverted to methionine with S-adenosylmethionine as the methyldonor?draw the structure of the tripeptife Pro-Ser-Cys as it would appear at physiological PH with its C-terminal amino acid residue protected as its methyl ester
- In pyrimidine nucleosides, the anti conformation predominates. Explain. Do the purine nucleosides have similar interactions?Given the fragment Ala-Lys-Tyr-Gly-Phe and Leu-Val-Ser-His-Cys-Arg, what is the expected result in both fragments with CuSO4 and NaOH? a. dark violet solution b. light violet solution c. blue solution d. colorless solutionWhy is Molisch's test used for the determination of the presence of pentose in the yeast RNA hydrolysate and what other tests could be used for this?
