urgent please answer both questions Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 3.0.H+N-CH2CHCOH*NH3Hhistidine• You do not have to consider stereochemistry.• You do not have to explicitly draw H atoms.• Do not include lone pairs in your answer. They will not be considered in the grading.▼n []? Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 7.3.tryptophanCH2CHCOH*NH3NHYou do not have to consider stereochemistry.• You do not have to explicitly draw H atoms.• Do not include lone pairs in your answer. They will not be considered in the grading.[

Amino acids:Amino acids are compounds which have both the amino group and carboxylic acid…

Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 3.0. H -CH2CHCOH N *NH3 H histidine You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading.

Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 3.0. H -CH2CHCOH N *NH3 H histidine You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins

Section26.SE: Something Extra

Problem 34AP: Using both three- and one-letter codes for amino acids, write the structures of all possible...

See similar textbooks

Similar questions

For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a p?a of 3 The amino group of alanine has a p?a of 8 Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7. __?__x10^?
Which amino acid has a net charge of +0.09 at pH 7? Show all calculations. Draw the structure of the amino acid that would predominate at this this pH. Circle all atoms that can be involved in making hydrogen bonds at pH 7
What is the name of this oligopeptide? Use the three letter and one letter nomenclature of the amino acids. Based on the charges on the peptide, what is the closest pH range would you expect that this was in? 2 to 4? 6 to 8? 10 to 12?
For the amino acid alanine, the major species in solution at pH 7 is the zwitterionic form, which has a negatively charged carboxylic acid group and a positively charged amino group. There is a less common neutral form in which neither group is charged. The carboxylic acid group of alanine has a p?apKa of 3.3. The amino group of alanine has a p?apKa of 8.8. Estimate the ratio of the concentration of the neutral amino acid species to the zwitterionic species at pH 7.
a) A solution of amino acid having carboxylic side chain was titrated against NaOH. If initial pH of the solution was 2.8. Describe the state of the functional groups of the amino acid at the initial pH and at 10.5.b) Briefly explain how you will separate amino acids mixture using the charge difference between the amino acids. c) A given glycine solution was titrated against NaOH and pH of the final solution was 4.8. Given that pKa1 and pKa2 of glycine are 2.34 and 9.60, respectively. Calculate the concentration of the dissociated amino acid in terms of the undissociated amino acid, if [x] and [y] are the concentrations of dissociated and undissociated amino acid, respectively.
Almost all proteins are composed from a set of about _____ amino acids.a. 4b. 10c. 20d. 50 ______ amino acids are considered essential.a. 5b. 10c. 15d. 20 An amino acid that has an indole group side chain.a. Trpb. Phec. Tyrd. ProWhich of the following is the simplest amino acid?a. Alab. Glyc. Vald. ProWhich of these will not give a blue solution with Ninhydrin testa. Prob. Phec. Alad. CysA neutral molecule with a positive and negative electrical charge.a. Isoelectric pointb. Zwitterionsc. Bufferd. Amphoteric3 amino acids joined together by two peptide bonds.a. Dipeptideb. Tripeptidec. Tetrapeptided. PolypeptideAn amino acid that can form disulfide bondsa. Cysteineb. Methioninec. Cystined. SerineWhich of the following is not a property of amino acidsa. Bufferb. Isoelectric pointc. Zwitterionsd. Insoluble in waterThe protein primary structure is held together bya. Hydrogen bondsb. Disulfide bondsc. Peptide bondsd. Protein bonds
Draw a structural formula for the form of amino acid most prevalent at pH 1.0. (a) Methionine
Draw Tryptophan in a peptide bond. Explain all of the bonds using valence bond theory (VBT). Next, explain where VBT fails and how molecular orbital theory is a better description of key regions of this amino acid and the peptide bonds it forms with other residues
If an amino acid has pKa1 = 2.71 and pKa2 = 9.31, at what pH value in aqueous solution would the predominant form of this amino acid be a zwitterion? Please explain your answer and show your work. a) 6.01 b) 2.71 c) 5.65 d) 12.02 e) 9.31
(In great detail) Valine (HV) is a diprotic amino acid with ?a1=5.18×10−3 and ?a2=1.91×10−10. Determine the pH of each of the solutions. A 0.303 M valine hydrochloride (H2V+Cl−) solution ph = ? A 0.303 M valine (HV) solution. ph = ? A 0.303 M sodium valinate (Na+V−) solution. ph = ?
For lysine and arginine, the isoelectric point, pI, occurs at a pH where the net charge on the nitrogen-containing groups is +1 and balances the charge of -1 on the a-carboxyl group. Calculate pI for these amino acids.
Why would a protein likely remain soluble at pH conditions either above or below the protein’s pI, but also become denatured under those same conditions ?