) Draw the Newman projection for the compound shown below, looking down the C3-C4 bond, in its conformation needed for an E2 elimination. Draw the E2 product of the reaction of this compound with a strong base. 15. CH3 Cl
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- Consider the E2 elimination of Compound A, and answer the following questions: (a) Label each stereocenter in Compound A with the correct R or S configuration. (b) Draw the structures of the major product with correct stereochemistry. Assume D and H have the same reactivity.Given that an E2 reaction proceeds with anti periplanar stereochemistry, draw the products of each elimination. The alkyl halides in (a) and (b) are diastereomers of each other. How are the products of these two reactions related?1a. Provide the products/reactants of the SN1 reactions below. Be very careful of the stereochemistry if applicable. (Recall that in SN1 reaction, the reactant’s chirality (aka configuration of the halo-carbon) is converted to both enantiomer – so you might need show both structures with dashed and wedge bonds 1b. Draw the mechanism (use curved arrow) of of EITHER c or d above
- If dehydration of 2-methylcyclohexanol were to occur under an E2 mechanism, draw the chair conformations of 2-methylcyclohexanol that would be necessary for the reaction to occur. 2-methylcyclohexanol is sold as a mixture of cis and trans isomersAlthough there are nine stereoisomers of 1,2,3,4,5,6hexachlorocyclohexane, one stereoisomer reacts 7000 times more slowly than any of the others in an E2 elimination. Draw the structure of this isomer and explain why this is so.which newman projection displays the proper antiperiplanar orientation for an E2 elimination of the reaction sequence below
- The E2 reaction is defined as stereoselective if the reacting alkyl halide contains? The E2 reaction is defined as regioselective if the reacting alkyl halide contains? only one β-hydrogen. two β-hydrogens attached to the same β-carbon atom. ...two β-hydrogens attached to different β-carbon atoms. ...no β-hydrogens.Draw an Energy diagram for an E1 reaction: (CH3)3CI + H2O ⇢ (CH3)2C=CH2+ H3O+ + I−a.Draw three-dimensional representations for all stereoisomers of 2chloro-3-methylpentane, and label pairs of enantiomers. b. Considering dehydrohalogenation across only C2 and C3, draw the E2 product that results from each of these alkyl halides. How many different products have you drawn? c. How are these products related to each other?
- Taking into account anti periplanar geometry, predict the major E2 product formed from each starting material.Draw a stepwise mechanism for the following reaction that illustrates how two substitution products are formed. Explain why 1-bromohex-2-ene reacts rapidly with a weak nucleophile (CH3OH) under SN1 reaction conditions, even though it is a 1° alkyl halide.The Hofmann product is favored by the E2 mechanism when 2-bromo-3-methylbutane is added: A. MeOH B. MeO:- in MeOH C. Nal in acetona D. (CH 3)3 CO:- in (CH 3),COH