Draw the products formed when each amine is treated with [1] CH3I (excess); [2] Ag:0; [3] A. Indicate the major product when a mixture results. CH3 a. CH3(CH2)6NH2 d. C. NH2 CH3 NH2 H.
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- What is the major Hofmann elimination product formed from each amine?What does the reaction of 4-Chloropentan-2-amine reacted with excess CH3l, Ag2O produce? O Hofmann product only O Zaitsev product only O Both Hofmann and Zaitsev products Equal distributionDraw the products formed when each amine is treated with [1] CH3I (excess); [2] Ag2O; [3] Δ. Indicate the major product when a mixture results.
- What 1° amine and carbonyl compound are needed to prepare each imine?Synthadotin is a promising anticancer drug in clinical trials. a.Identify the functional groups. b.Classify any amine or amide as 1°, 2°, or 3°. c.At which sites can synthadotin hydrogen bond to another molecule like itself? d. Label two nucleophilic sites. e. Label two electrophilic sites. f. What product is formed when synthadotin is treated with HCl?Stanozolol is an anabolic steroid that promotes muscle growth. Althoughstanozolol has been used by athletes and body builders, many physicaland psychological problems result from prolonged use and it is bannedin competitive sports. Explain why the pKa of the N—H bond in the pyrazole ring iscomparable to the pKa of the O—H bond, making it considerably moreacidic than amines such as CH3NH2 (pKa = 40).
- Draw the product formed when phenylacetic acid (C6H5CH2COOH) is treated with each reagent. With some reagents, no reaction occurs. a. NaHCO3 b. NaOH c. SOCl2 d. NaCl e. NH3(1equiv) f. NH3, ∆ g. CH3OH, H2SO4 h. CH3OH, −OH i. [1] NaOH; [2] CH3COCl j. CH3NH2, DCC k. [1] SOCl2; [2] CH3CH2CH2NH2 (excess) l. [1] SOCl2; [2] (CH3)2; [2] (CHDraw the product formed when pentanal (CH3CH2CH2CH2CHO) is treatedwith following reagent. With some reagents, no reaction occurs. Ag2O, NH4OHDraw the products when phenylacetic acid (C6H5CH2COOH) is treated with each reagent. With some reagents no reaction occurs: A)NaCl B)NH3(1 eqiv) C)1)CH2NH2, 2)CH3COCl
- Amino acids such as glycine are the building blocks of large molecules called proteins that give structure to muscle, tendon, hair, and nails. a.) Explain why glycine does not actually exist in the form with all atomsuncharged, but actually exists as a salt called a zwitterion. b.) What product is formed when glycine is treated with concentratedHCl?c.) What product is formed when glycine is treated with NaOH?Which have higher imfa? Water or ethanol? Why?What carboxylic acid and amine are needed to synthesize the pain reliever phenacetin? Phenacetin was once a component of the over-the-counter pain reliever APC (aspirin, phenacetin, caffeine), but it is no longer used because of its kidney toxicity.