Drivers are mutations that drive the cancer process; passengers are mutations that arise randomly in the process of tumor development and do not contribute to the progression of cancer. How might researchers go about distinguishing between drivers and passengers? Propose some different approaches.

Q: Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb?  If so, how…

A: The process by which a cell gives rise to two identical daughter cells is referred to as cell…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Induced pluripotent stem cells (iPS) is a type of stem cell(pluripotent) in nature that is derived…

Q: one question with multiple parts! 1A) If you were a cancer biologist interested in developing new…

A: Introduction Metastasis Is The Spread Of A Pathogenic Agent From An Initial Or Main Site Inside The…

Q: Mutations in three broad classes of genes have been implicated in the onset of cancer. Can you…

A: A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic…

Q: What are Two kinds of cancer-producing mutations?

A: Cancer is defined as any one of a large number of diseases characterized by the development of…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: What are the biggest challenges that mutations pose to oncologists and cancer biologists who seek to…

A: Mutations are one of the biggest challenges to the Oncologists and cancer biologists who wish and…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Genetic transformation happens when the genetic composition of an organism is transformed by the…

Q: Is there a possibility that by manipulating the microenvironment, we could disrupt the signals…

A: Mutator phenotype is seen in cancer cells. This condition is caused by mutations in genes that are…

Q: Which of the following is NOT an example of fail-safe mechanisms that prevent the irregular cell…

A: Cancer is the uncontrolled cell division where he ell continuously divides. Cancer cells thus become…

Q: For many years, targeted therapies for cancer treatment continue to be developed, however more and…

A: Targeted therapy is a type of cancer treatment that uses drugs designed to "target" cancer cells…

Q: If cancer is fundamentally a genetic disease, how might an environmental factor such as smoking…

A: Tumor is a mass of tissues. It may be benign or malignant. The cellular growth that occurs when the…

Q: What is the cancer stem cell hypothesis?

A: Every living organism is made up of cells. A cell is a small self-contained unit within a whole…

Q: Why do mutations in DNA repair genes increase the likelihood of developing cancer?

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that transfers genetic information from one…

Q: Which of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin…

A: Introduction- Cancer is a caused by the disturbances in the  controls which regulate cells and this…

Q: The current way to gauge the effectiveness of chemotherapy is to track the size of the tumor. If the…

A: Introduction : The use of  different combination of drugs in the treatment of cancer is referred to…

Q: For a gene to be cancer-inducing, both copies of the gene must be affected, explain it with example.

A: Cancer inducing gene The gene having the potential to cause cancer are called as cancer inducing…

Q: Which is a.) Reduction of cancer risks b.) Correction of cancer genes or c.) Destruction of cancer…

A: Cancer is a disease caused by the uncontrolled proliferation of cells due to the defects in the cell…

Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?

A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…

Q: Discuss the interplay between genetics and environment in the development of cancer (it would be…

A: Research on several diseases have found that the cause of diseases are not only environmental or…

Q: What is/are the role/s of molecular techniques in understanding cancer? Cite some references from…

A: In cancer, cells grow abnormally. Cancer is not one disease. It is a group of diseases. The…

Q: Cancer often results from a multistage process involving an initiating event (mediated by a viral…

A: Phorbol esters are a group of chemicals that are found in many plants. They are the ester…

Q: Unlike many other diseases, the vast majority of cancers in humans are not transmissible - meaning a…

A: Cancer is "referred" to as any abnormal growth of cell tissue. Cancer can develop anywhere in the…

Q: How do normal cells protect themselves from accumulating mutations in genes that could lead to…

A: Studies reveal that the p53 protein instructs cells to under-go apoptosis when mutations in the DNA…

Q: relationship that may exist between mutations and cancer

A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…

Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…

A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…

Q: Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?

A: Biotechnology is a wide range of studies where it uses its techniques with biological systems to…

Q: rds, explain metastasis and why this process is important in the prognosis of a patient, and is this…

A: There are different kinds of cancer. A tumor can be cancerous or it can be benign. It is caused by…

Q: Give a possible explanation for why a mutation in a single gene does not always lead to cancer.

A: Mutation in a gene is defined as any change or alteration in the structure, and hence, function of…

Q: What separates cancer cells from normal cells?

A:

Q: proto-oncogenes and tumor suppressor genes cause most types of cancer

A: The genes are formed by the Deoxyribonucleic acid (DNA) of an organism. These genes code all of the…

Q: What types of evidence indicate that cancer arises from genetic changes?

A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of the…

Q: Sequencing the human genome, the development of microarray technology, and personal genomics promise…

A: To describe: How are Sequencing the human genome, the development of microarray technology, and…

Q: Mutations that increase the creation of blood vessels and turn on expression of telomerase are....…

A: Reactivation of telomerase could be valuable in certain types of cell treatment and doesn't seem…

Q: EXPLAIN BRIEFLY: Explain the molecular mechanisms of cancers caused by a P53 gene mutation.

A: Answers P53 also defined as tumour suppressor Gene. Hence it protect the cells from various damages…

Q: Part A and B A. What are the Hallmarks of Cancer? A) Criteria that are used to identify tumors in…

A: The hallmarks of cancer are the biological capabilities that are required during the development of…

Q: Radiotherapy (treatment with ionizing radiation) is one of the most effective current cancer…

A: A Radiation therapy is used to treat cancer. This therapy uses intense energy like X-rays to target…

Q: Discuss the concept of cancer survivorship ?

A: Survivorship in cancer refers to the health and well-being of a cancer patient from the time of…

Q: Which of the following is an enabling characteristic for cancer that can increase the likelihood of…

A: The somatic mutations in the genome of a cancer cell, irrespective of their structural nature, can…

Q: What is the role of regulatory gene mutations in cancer?

A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…

Q: Explain how our understanding of the molecular basis of cancer has been used to develop new…

A: Hippocrates a Greek physician described cancer as ulcer-forming and non-ulcer-forming carcinoma,…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: induced pluripotent stem cells are the type of stem cells that are produced from the somatic cells…

Q: Would a drug that induced apoptosis or one that induced necrosis be preferable for treatment of…

A: INTRODUCTION Flowcytometry Flowcytometry is a technique that simultaneously measures and analyse…

Q: how can mutations in several genes drive cancer?

A: Ans: Mutation: The change in the nucleotide sequence base level (single base) is referred to as…

Q: Discuss the challenges of producing anticancer drugs that counteract the effects of mutations in…

A: Tumor suppressor genes are the genes that decline the cell division process, acts in programmed cell…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.