What are the biggest challenges that mutations pose to oncologists and cancer biologists who seek to find novel cures against cancers?

Q: How can a defect in p53 gene contribute to cancer development?

A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…

Q: What is the link between epigenetics and cancer?

A: Epigenetics is considered as the study in which the gene shows its behavior according to the…

Q: How can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the…

A: Epigenetics is the study of various alterations in an organism occurred because of certain gene…

Q: Should genetic testing for cancer be availablefor everyone, or should genetic testingbe confined to…

A: Cancer is an abnormal proliferation of body cells that has undergone mutation. The cancer is of…

Q: What would make someone think they might have developed cancer and seek medical testing?

A: Cancer is a medical condition in which cells become abnormal and divide uncontrollably which leads…

Q: What are Two kinds of cancer-producing mutations?

A: Cancer is defined as any one of a large number of diseases characterized by the development of…

Q: Why is this system promising in curing cancer and genetic diseases? What are some of the…

A: Introduction Gene therapy involves changing the genetic instructions within a person's cells to…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…

A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…

Q: If cancer is fundamentally a genetic disease, how might an environmental factor such as smoking…

A: Tumor is a mass of tissues. It may be benign or malignant. The cellular growth that occurs when the…

Q: What is the cancer stem cell hypothesis?

A: Every living organism is made up of cells. A cell is a small self-contained unit within a whole…

Q: Why do mutations in DNA repair genes increase the likelihood of developing cancer?

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that transfers genetic information from one…

Q: How can cancer arise from stem cells?

A: Stem cells are unique human cells and can grow into several cell types. This can vary between cells…

Q: What is the relationship between genetic mutations and cancer?

A: Mutation is defined as change in nucleotides nitrogenous base.

Q: What genes are involved in cancer?

A: Genes Involved In Cancer --- Genes  and Their Characteristics -- Genes are made up of pieces of DNA…

Q: What are the requirements for normal cell division? What are the requirements for cancer cells…

A: Mutation is defined as an erroneous change within the gene sequence of an organism that leads to a…

Q: How is DNA methylation related to cancer?

A: The alteration to the structure of chromatin affects the gene expression, which is known as…

Q: How do normal cells protect themselves from accumulating mutations in genes that could lead to…

A: Studies reveal that the p53 protein instructs cells to under-go apoptosis when mutations in the DNA…

Q: How do oncogenes differ from tumor suppressor genes?

A: Oncogenes are a physically and functionally diverse set of genes, the protein products of which act…

Q: Cancer can arise spontaneously, but it can also be induced as a result of environmental factors such…

A: Cancer is a collection of diseases characterized by abnormal and uncontrolled growth. Cancer arises…

Q: How Mutations Cause Cancer Phenotypes?

A: The medical condition of cancer is generally characterized by the presence of a cluster of cells…

Q: relationship that may exist between mutations and cancer

A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…

Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…

A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…

Q: How do we know that many cancer-causing agents (carcinogens)are also mutagenic?

A: A large number of chemicals and several physical agents, such as UV light and γ-radiation, have been…

Q: How do stem cells retain this capacity, and can we harness it to cure debilitating diseases?

A: Stem cells: Stem cells are the cells that have the potential to develop into different types in the…

Q: How oncogenes contribute to cancer?

A: Cancer:       It is a disease where cells divide abnormally and damage other cells. There are…

Q: Let’s suppose you were interested in developing drugs to preventepigenetic changes that may…

A: Genes are basic physical and functional unit of heredity. It is a part of DNA that has instruction…

Q: What separates cancer cells from normal cells?

A:

Q: What technique is used to identify genes involved in cancer formation ?

A:

Q: What type of epigenetic changes are associated with cancer?

A: Epigenetic changes or modifications are important for maintenance of tissue specific gene…

Q: How tumor-suppressor mutations contribute to cancer?

A: Cancer - Cancer is a type of disease in which cells divide in an uncontrolled manner. The cells…

Q: What types of evidence indicate that cancer arises from genetic changes?

A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of the…

Q: Sequencing the human genome, the development of microarray technology, and personal genomics promise…

A: To describe: How are Sequencing the human genome, the development of microarray technology, and…

Q: How does the normal p53 protein inhibit cancer development?

A: Tumor-suppressor genes code for proteins that repair damaged DNA (preventing a cell from turning…

Q: Mutations that increase the creation of blood vessels and turn on expression of telomerase are....…

A: Reactivation of telomerase could be valuable in certain types of cell treatment and doesn't seem…

Q: What could cause cancer in our natural environment? Or what activities do we carry out that could…

A: Cancer: Cancer is the condition of  uncontrolled growth of abnormal cells anywhere in a body. These…

Q: What is a tumor suppressor? What is an oncogene?

A: Cancer is a diseased condition where the cells show abnormal growth and proliferation. The cancerous…

Q: How to do a cancer data dictionary?

A: The cancer data dictionary is a cluster of information about a cancer diagnosis. The data is…

Q: How do radiation and chemical mutagens cause DNA damage?

A: Mutagen It is the factor that cause irreversible and heritable change in the genetic material means…

Q: Discuss the concept of cancer survivorship ?

A: Survivorship in cancer refers to the health and well-being of a cancer patient from the time of…

Q: What are the two principal opposing views regarding the patenting of genes?

A: Gene patent is a patent on a specific isolated gene sequence, a natural sequence that has been…

Q: Which of the following is an enabling characteristic for cancer that can increase the likelihood of…

A: The somatic mutations in the genome of a cancer cell, irrespective of their structural nature, can…

Q: How can mutations in noncoding segments of DNA contribute to the development of cancers?

A: The functions segment of hereditary material that mainly codes for the proteins is a gene. The…

Q: What is the role of regulatory gene mutations in cancer?

A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…

Q: how can mutations in several genes drive cancer?

A: Ans: Mutation: The change in the nucleotide sequence base level (single base) is referred to as…

Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…

A: Given: Role of p53 and RAS protein to stop a cancer cell from replication. What happens if mutation…