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- What is the strongest nucleophile, NH3, CH4, CH3O-, or H2O?For SN1 Explain the order in which 1o (primary) alkyl halides reacted (fastest to slowest) and explain why. The 1o primary alkyl halides are: (see picture below) 1-chlorobutane 1-bromobutane 1-chloro-2butene benzylchlorideRank the following molecules in order of increasing relative rate of SN1 Solvolysis with methanol and heat
- Rank the following species from best nucleophile to poorest nucleophile in an aqueous solution:From each pair, select the stronger nucleophile. Q.) CH3SH or CH3S-Trimethylphosphine is a stronger nucleophile than triphenylphosphine, but it is rarely usedto make ylides. Why is trimethylphosphine unsuitable for making most phosphorus ylides?
- Order the following alkyl halides according to their decreasing rate in an E2 using KOtBu. 1 is the fastest and 4 is the lowest.Identify the stronger nucleophile in each pair. a.NH3, −NH2 b.CH3NH2, CH3OH c.CH3CO2−, CH3CH2O−Would you expect acetate ion (CH3CO2 -) to be a better nucleophile in an SN2 reaction with an alkyl halide carried out in methanol or in dimethyl sulfoxide