Erythromycin is a weak base with a pka of= 5.2 What will be the ionisation state of the drug in stomach, small intestine and blood? what is the site of absorption of this drug? pH stomach = 1.5, pH blood = 7.4, pH of small intestine is 6.5. %3D %3D

Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter16: Principles Of Chemical Reactivity: The Chemistry Of Acids And Bases
Section16.10: The Lewis Concept Of Acids And Bases
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Erythromycin is a weak base with a pka of= 5.2
What will be the ionisation state of the drug in stomach, small
intestine and blood? what is the site of absorption of this drug?
pH stomach = 1.5, pH blood = 7.4, pH of small intestine is 6.5.
Transcribed Image Text:Erythromycin is a weak base with a pka of= 5.2 What will be the ionisation state of the drug in stomach, small intestine and blood? what is the site of absorption of this drug? pH stomach = 1.5, pH blood = 7.4, pH of small intestine is 6.5.
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