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explain how p53 functions in a cell that sustained DNA damage to prevent progression of that cell into a cancer cell
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- Explain the difference between a proto-oncogene and a tumor suppressor gene.Explain the role of p53 protein in protecting normal cells against cancer. With respect to this protein and its function, explain how a normal cell turns cancerous.Describe how tumor suppressors function to stop the cell cycle until certain events are completed
- Explain why p53 is mutated in the vast majority of human cancers.Describe the roles of proto-oncogenes and tumor suppressor genes in controlling cell growth, and discuss how some viruses can circumvent this control.A mutation in p53 promoter that prevents p53 from being expresses Causes? Why? A. Increased proliferation B. Decreased proliferation
- Describe how is cancer related to cell cycleExplain why the continually active CDK will most likely change the normal cells into cancer cells.Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and how might gene therapy or other drug interventions inhibit the growth of a tumor?