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A: Why lactose can not be used to replace IPTG? IPTG:- isopropyl thiogalactopyranoside usually mimic…
Q: DNA or RNA or DNA & RNA
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A: The cardiac conduction system includes special muscle fibers.
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Q: Q4
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A:
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A:
Q: What diagnostic tests are used to evaluate cardiac structure and function?
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Q: "Transcriptome Analysis Reveals Profiles of Expressed Genes in Cellsand Tissues". Define this ?
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Q: How do platelets and factors of the clotting cascade contribute to hemostasis?
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Explain the mechanisms of disease development that result from or cause geneexpression changes in cells. ?
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- Theodor Boveri predicted that malignancies would often be associated with chromosomal mutation. What lines of evidence substantiate this prediction?Describe how different types of chromosomalrearrangements alter gene expression patterns orgenerate new gene productsexplain which controls over gene expression are likely to be very brief, which may be long lasting, and why they differ?
- Mutations outside the coding sequences can modify geneexpression by altering the amount, time, or place of__________ production.?Explain about the Identification and Cloning of the Huntington Gene ?What is a gene knockout? Is an animal or plant with a gene knockout a heterozygote or homozygote? What might you conclude if a gene knockout does not have a phenotypic effect?
- What is mutation? Distinguish between (i) neutral and silent mutation (ii) germ line and somatic mutation (iii) Trisomy 21 and Trisomy XExplain Using Drosophila transgenes to link a mutant phenotype to a geneAccording to the multi-hit model, more than one mutation must occur in a cell for cancer to develop. Once an oncogene has been formed by a mutation, what other type of gene must also mutate?
- Provide one example of a clinical implication of a “silent mutation” that has proven to have an effect onthe phenotype and provide a brief description of its molecular characteristics?explain Mapping genes by cotransductionfrequencies.(a) How does the duplication of individual genes occur? (b) individual that inherit a genetic condition known as xeroderma pigmentosum exhibit an extreme sensitivity to sunlight exposure and often develop skin cancer by the age of 10. What repair pathway is most likely disrupted as a result of such mutation? Explain why?