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Explain the Retrotransposons—the Copia –White-Apricot System in Drosophila ?
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- Why is it that mutations in bicoid and nanos exhibit genetic maternal effect in Drosophila (a mutation in the maternal parent produces a phenotype that shows up in the offspring), but mutations in runt and gooseberry do not?Explain the X-Linkage in Drosophila ?What would be the most likely effect of inhibiting the translation of hunchback mRNA throughout a Drosophila embryo?
- Describe the appearance of a Drosophila embryo, in which the knirps gene protein-coding sequence has been replaced by lacZ, following incubation in a solution of X-gal.Prior to the work described here, what was the original purpose ofMorgan’s experiments with Drosophila?The locations of six deletions have been mapped to a Drosophila chromosome, as shown in the following deletion map. Recessive mutations a, b, c, d, e, and f are known to be located in the same region as the deletions, but the order of the mutations on the chromosome is not known.
- Explain how the Sxl promoter “counts” the number of Xchromosomes in Drosophila.What would you predict to be the phenotype of a Drosophila larva whose mother was homozygous for a loss-of-function allele in the nanos gene?What is positional information? Discuss three different ways that cells obtain positional information. Which of these three ways do you think is the most important for the formation of a segmented body pattern in Drosophila?