Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the safety of a drug candidate. Explain this at your own words

Q: Give 5 importance of studying toxicology and how does toxicity develop

A: Toxic substance There are many substances that have the potential to produce toxic effect or injury.…

Q: The major characteristics of chemical control agents as a group include: (Select all that apply) O…

A: Major characteristics of chemical control agents.

Q: Explain the role of LC50 in ensuring the safety of a drug candidate? Explain at your own words

A: Drugs are defined as the type of chemical substances where they produce changes in the physiology or…

Q: What is a crude drug? Describe the sources of drugs.

A: Crude Drug means they are present in the natural organic or inorganic environments or in natural…

Q: Define therapeutic index and explain its importance.

A: Therapeutic Index is also known as Therapeutic Ratio. It is a quantitative measurement of the…

Q: Explain the role of  toxicological parameters LD50 in ensuring the safety of a drug candidate.…

A: Toxicological parameters - It is the level of toxicity to determine drug usage. The toxicological…

Q: mention six ways in which the drugs containers can be  catered for.

A: A drug is a molecule which might resemble a organic molecule inside the body or an exogenous…

Q: Explain, in your own words, the difference between an adverse effect, a poisoning, and a toxic…

A: All the given terms are associated with negative events occurring following intake of a subastance,…

Q: Identify which categories of drugs are most selectively toxic and why.

A: An antibiotic is a sort of antimicrobial substance dynamic against microbes. It is the main sort of…

Q: Discuss ARV Drugs

A: Antiretroviral drugs (ARVs) are mainly used in the treatment of infections caused by the human…

Q: What are the different component of therapeutic index. Define its clinical relevance

A: therapeutic index: The dosage range at which a medicine is effective without causing unacceptably…

Q: Which of the statements below about generics drugs are true? Select one or more: a. The active…

A: Generic drugs are the drug substances that are not marketed by brand names but are marketed by their…

Q: xplain how alcohols work as antimicrobials and describe their limitations to effectiveness.

A: Antimicrobial are known as an agent that either kills or inhibits the growth of micro-organisms.…

Q: Explain the term low therapeutic index.

A: Therapeutic index is the window of dosage of that drug in which it is therapeutically effective,…

Q: Summarize the primary reasons that we find ourselves in a “drug dilemma” with regard to…

A: Antimicrobial drugs are chemical substances of natural or synthetic origin that suppress the growth…

Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…

A: A drug is any substance that can affect psychology or physiology when taken into the body. It is…

Q: List and describe the different levels of effectiveness of germicidal chemicals.  In that…

A: Germicidal chemical is something (such as an antiseptic or disinfectant) that destroys or…

Q: Discuss the factors governing the route of drug administration with examples.

A: The reason for option of routes of medication administration are governing by many factors:…

Q: Using a schematic diagram, illustrate the process of the following stages of drug development:…

A: Stage 1: Discovery and Development:Drug disclosure is the manner by which new prescriptions are…

Q: Discuss both intrinsic and environmental factors influencing the biotransformation of drugs. (20…

A: Biotransformation of medications to polar metabolites is a main step in the cessation of procedure…

Q: Summarize the primary reasons that we fi nd ourselves in a “drug dilemma” with regard to…

A: Unwanted side effects can occur as a result of a doctor's advice, prescriptions, or treatments,…

Q: Explain the major mechanisms by which microbes becomeresistant to drugs.

A: Antimicrobial resistance refers to the condition that occurs when microorganisms such as bacteria,…

Q: Identify the general categories of the cellular targets of physical and chemical agents.

A: A cell is the basic unit of life that eventually assembles into a whole creature. A cell contains a…

Q: What are TAMLs? Describe their role in environmental Toxicology

A: Environmental toxicology is the branch of science that deals with the harmful effects of various…

Q: Describe the factors that affect both drug absorption and bioavailability.

A: Drug absorption : The most important principle in pharmacokinetics theory is drug absorption. The…

Q: Why are animals used in laboratory experiments in toxicology? Explain the dose-response curve. Why…

A: Animals have typically been utilised in scientific tests to avoid ethical quandaries associated with…

Q: Discuss medical considerations in fi nal drug selection.

A: According to rational medicine uses, patients are given pharmaceuticals suited to their healthcare…

Q: metal control agents and describe their most common applications.

A: Heavy metals can be used as antimicrobial agents. many samples of significant metals are silver,…

Q: Give 3 examples of Antiseptic and 3 disinfectant use at home, in clinics, and in Hospital

A: Both antiseptics and disinfectants are cleaning agents. A same substance can be used either as an…

Q: Define toxicology dose and response

A: Toxicology Dose response curve is defined as the response of target host to various doses of toxic…

Q: Name some pharmacology math conventions that have been instituted to keep patients safer.

A: Mathematics always plays a vital role in most sectors of society. In the field of nursing and…

Q: Draw and explain the conceptual pathway of mechanism, transport and excretion of drugs. (subject:…

A: In pharmacology, drugs are defined as chemical substances or compounds used as medicines, which…

Q: Enumerate the different sources of drug. Provide example for each source. Discuss the advantages and…

A: Sources of drugs Natural sources Plants Animals Microbes Minerals Artificial sources Synthetic Semi-…

Q: Which option best represents the ideal characteristics of drugs for use in low- and middle-income…

A: Introduction Substances That Alter A Person's Mental Or Physical State Are Known As Drugs. They Can…

Q: Summarize the problems in managing antimicrobial drugs.

A: A disease is a state of unhealthiness of the physical body, mind and social interaction. A disease…

Q: different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the…

A: Toxicology helps us to understand the harmful effects of the chemicals,  on the people and…

Q: Discuss the study of chemical hazards and their effects,including wildlife toxicology, epidemiology,…

A: Toxicants can be both organic and manmade, and there are hundreds of synthetic compounds in our…

Q: Name four categories of cellular targets for physical and chemical agents.

A: Introduction: Physical and chemical agents are employed in microbial control. disinfection,…

Q: Describe three situations where you would use an excipient in your drug formulation and how you…

A: Excipients can be outlined as inert substances that are utilized in the drugs as diluents.…

Q: Choose the combination of answers that most accurately completes the statement. An antimicrobial…

A: The therapeutic index refers to the ratio that is used to quantitatively measure the relative safety…

Q: Role of different toxicological parameters (like ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring…

A: Toxicology is the study of harmful effects of chemical substances, pharmaceutical drugs, and other…

Q: Explain the role of  toxicological parameters LOAEL in ensuring the safety of a drug candidate.…

A: In the development of a new drug, it is very important make sure about the safety profile of the…

Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.