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- Organic Chemistry II: How do we know which direct the reaction? Why Methoxy Functional Group direct the reaction instead of fluorine? Is it something to do with electronegativity ? Or is it something to do with withdrawing group?? How do we know if a gourp is more withdrawing ??????K15. rank from weakest to strongest Bronsted base. Please give explanation and what the rankings look like for this questionKindly share detailed explanation for each step and each options