) For your assigned letter rank the molecules provided from lowest (1) to highest (3) based on their reactivity with a nucleophile in a nucleophilic addition-elimination type reaction. Explain your ranking. А В А.
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- p-Fluoronitrobenzene is more reactive toward hydroxide ion than is p-chloronitrobenzene. What does this tell you about the rate-determining step for nucleophilic aromatic substitution?Define the General Mechanism–Acid-Catalyzed Nucleophilic Addition ?Given a target molecule below, propose a synthetic route involving either the Wittig reaction or HornerEdmonson approach. Justify your choice, considering both reagents and selectivity
- Please I need help with this question Based on the experiment- Synthesis of Iodosalicylamide – An Electrophilic AromaticSubstitution (a derivative of benzene, salicylamide was used and substituted an iodine atom onto the ring; the ring is the nucleophile while the atom/molecule that is being substituted onto the ring has anelectrophilic character) Please I need help with this QUESTION: Draw the structure of the final product(s) based on the ATTACHED IR analysis. Also label the signals (both the frequency and molecular motion) that help determine the final product(s). Thanks in advanceStep 2 of the iodination of benzene shows water acting as a base and removing a proton from the sigma complex. We did notconsider the possibility of water acting as a nucleophile and attacking the carbocation, as in an electrophilic addition to an alkene.Draw the reaction that would occur if water reacted as a nucleophile and added to the carbocation. Explain why this type ofaddition is rarely observed.Decide which compounds from the list below are best suited for nucleophilic addition reactions and which ones are more appropriate for nucleophilic substitution reactions.
- Please provide 3 possible mechanisms for bromination of trans-cinnamic acid and pyridinium tribromide (Br2) with stereochemistry (wedge and dash bond) (1 for anti addition, 1 for syn addition, and 1 for 50:50 syn and anti additon).Arrange the structure on the image with regard to the reactivity towards nucleophilic acyl substitution 1 being the least and 3 being the mostFrom 1 being the slowest and 4 being the fastest rank the aromatic hydrocarbons in terms of increasing raters of nitration via electrophilic aromatic substitution
- Determine which nucleophilic aromatic substitutions are likely, and proposemechanisms for both the addition–elimination type and the benzyne type.In the chemical reaction between crotyl chloride and ethanolic silver nitrate solution, a precipitate is definitely formed. Using the skeletal structures of the molecules, write out the skeletal structure of each reaction (don't include the mechanism). Identify what the nucleophile is in each type of reaction, especially within this SN1 reaction. Explain the reactivity of each electrophile/substrate in terms of whether they are tertiary, secondary, primary, etc. for each reaction. Include the overall chemical reaction.In the chemical reaction between benzyl chloride and ethanolic silver nitrate solution, a precipitate is barely formed. Using the skeletal structures of the molecules, write out the skeletal structure of each reaction (don't include the mechanism). Identify what the nucleophile is in each type of reaction, especially within this SN1 reaction. Explain the reactivity of each electrophile/substrate in terms of whether they are tertiary, secondary, primary, etc. for each reaction. Include the overall chemical reaction.