GABA is commonly introduced as the most prominent inhibitory neurotransmitter in our brains. However, scientists have discovered that GABA does not always lead to the inhibition of a postsynaptic neuron. Explain how this is possible for neurotransmitters more generally. In other words, describe how it is possible for the same neurotransmitter to cause either a depolarizing or hyperpolarizing effect at different postsynaptic synapses. Make sure you clearly explain the reasoning behind your answer.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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3. GABA is commonly introduced as the most prominent inhibitory neurotransmitter in our
brains. However, scientists have discovered that GABA does not always lead to the
inhibition of a postsynaptic neuron. Explain how this is possible for neurotransmitters
more generally. In other words, describe how it is possible for the same neurotransmitter
to cause either a depolarizing or hyperpolarizing effect at different postsynaptic synapses.
Make sure you clearly explain the reasoning behind your answer.
Transcribed Image Text:3. GABA is commonly introduced as the most prominent inhibitory neurotransmitter in our brains. However, scientists have discovered that GABA does not always lead to the inhibition of a postsynaptic neuron. Explain how this is possible for neurotransmitters more generally. In other words, describe how it is possible for the same neurotransmitter to cause either a depolarizing or hyperpolarizing effect at different postsynaptic synapses. Make sure you clearly explain the reasoning behind your answer.
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