Given that you have an even-skipped mutant (Drosophila) which results in the loss of stripe #5, describe an experiment that you could devise to reintroduce/rescue the mutation.
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Given that you have an even-skipped mutant (Drosophila) which results in the loss of stripe #5, describe an experiment that you could devise to reintroduce/rescue the mutation.
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- When doing a lab that involves Extraction of Genomic DNA from adult Drosophila melanogaster. - What are the controls you should use and why use these?What would you predict to be the phenotype of a Drosophila larva whose mother was homozygous for a loss-of-function allele in the nanos gene?Here are schematic diagrams of mutant Drosophila larvae. The left side of each pair shows a wild-type larva, with gray boxes showing the sections that are missing in the mutant larva. Which type of gene is defective in each larva: a gap gene, a pair-rule gene, or a segment-polarity gene?
- In a particular strain of Neurospora, a poky mutation exhibits biparental inheritance, whereas poky mutations in other strains are inherited only from the maternal parent. Explain these results.Explain why loss-of-function hedgehog and smoothened mutations yield the same phenotype in flies, but a loss-of- function patched mutation yields the opposite phenotype.Usually, the mutant alleles studied in Drosophila experiments are recessive because: A. they are difficult to create. B. they are loss of function mutations. C. they do not survive as long as dominant alleles. D. they do not occur in wild-type flies.
- How can you determine whether a phenotype such as reduced eyes in fruit flies is due to a recessive mutation or is a phenocopy?Suppose that you are studying the role of Protein B, which you believe plays a role in regulating PCD/Apoptosis in mice. You create two lines of mutant mice. One (bb) is homozygous for a loss-of-function allele of gene B. The other (Bb) is heterozygous, with one wild-type allele and one loss-of function allele. Initially you pay particular attention to two phenotypes of the resulting mice:(i) The morphology of their paws (see picture) (ii) The size of their brains & shape of their skulls. The bb mice have unusually large brains and unusual protrusions from their skulls. Based on these data, does it appear that Protein B, when present and active, favors or inhibits PCD/Apoptosis?Briefly explain your reasoning. The answer should address both the paw and brain/skull data.For the first experiment ever on Drosophila mutations. Answer the following questions. a. What is the title of the first published paper explained the experiment and what is the name of the Author? b. What is the first mutation discovered in Drosophila? c. Explain the changes in the Drosophila yellow mutant (Y)compared to wild type.
- "Coat color in rats varies from white to black and includes many shades of gray in between. If the number of different coat colors possible is 9, how many genes are involved? "How can you use this piece of information to help you explain to your friends what is the significance of mutations in the emergence of new genetic properties (alleles) that may result (or not) in new phenotypic characteristics? (Recall that not all SNPs affect phenotype.)Show how breeding females of the vermilion/brown, cinnabar/brown, and scarlet/brown double mutants with males of the scarlet strain (instead of the cinnabar strain) would have also enabled us to differentiate between the three double mutant Drosophila strains. Include the genotypes of the breeding partners and the offspring, and the phenotypes of the offspring dont copy from any other site asap please