Glucose-6-phosphate dehydrogenase catalyzes the first step of the pentose phosphate pathway. This enzyme is highly specific for NADP+; the KM for NAD+ is about a thousand times that of NADP+. What does this mean in terms of affinity of the enzyme for NAD+ and NADP+? How would being forced to use NAD+ affect rate?
Glucose-6-phosphate dehydrogenase catalyzes the first step of the pentose phosphate pathway. This enzyme is highly specific for NADP+; the KM for NAD+ is about a thousand times that of NADP+. What does this mean in terms of affinity of the enzyme for NAD+ and NADP+? How would being forced to use NAD+ affect rate?
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter2: Cell Physiology
Section: Chapter Questions
Problem 10RE: Using the answer code on the right, indicate which form of energy production is being described: 1....
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Glucose-6-phosphate dehydrogenase catalyzes the first step of the pentose phosphate pathway. This enzyme is highly specific for NADP+; the KM for NAD+ is about a thousand times that of NADP+. What does this mean in terms of affinity of the enzyme for NAD+ and NADP+? How would being forced to use NAD+ affect rate?
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