Glycolysis involves ten biochemical reactions. The first two reactions of the glycolysis cycle are : (1) C6H12O6(aq) + ATP(aq)  G6P(aq)+ ADP(aq)    ΔH1 = -19.74 kJ.mol-1 and K1 = 4.6 × 10-3 at 37°C (2)                     G6P(aq)  F6P(aq)                      ΔH2 = -2.84 kJ.mol-1 and K2 = 2.8 × 10-1 at 37°C Calculate the equilibrium constant for the reaction producing F6P and ADP from C6H12O6 and ATP. Calculate the equilibrium concentration of F6P(aq) generated by glycolysis in a normal body at 37°C, starting with 1.20 × 10-6L-1 glucose, 1.00 × 10-4 mol.L-1 ATP, and 1.00 × 10-2 mol.L-1 ADP. During a fever, the body temperature will increase. Will the concentration of F6P increase or decrease?

Chemistry: The Molecular Science
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Chapter4: Energy And Chemical Reactions
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  1. Glycolysis involves ten biochemical reactions. The first two reactions of the glycolysis cycle are :

(1) C6H12O6(aq) + ATP(aq)  G6P(aq)+ ADP(aq)    ΔH1 = -19.74 kJ.mol-1 and K1 = 4.6 × 10-3 at 37°C

(2)                     G6P(aq)  F6P(aq)                      ΔH2 = -2.84 kJ.mol-1 and K2 = 2.8 × 10-1 at 37°C

  1. Calculate the equilibrium constant for the reaction producing F6P and ADP from C6H12O6 and ATP.
  2. Calculate the equilibrium concentration of F6P(aq) generated by glycolysis in a normal body at 37°C, starting with 1.20 × 10-6L-1 glucose, 1.00 × 10-4 mol.L-1 ATP, and 1.00 × 10-2 mol.L-1 ADP.
  3. During a fever, the body temperature will increase. Will the concentration of F6P increase or decrease?
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