Heroine is too toxic for clinical use Fentanyl can be administered transdermally Morphine supresses pain by reducing histamine release in inflamed tissue Naloxone is used to treat opioid addiction Morphine is acid labile and must be given parenterally

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Amines

Amines are organic compounds with a nitrogen atom having a lone pair of electrons on it. They are derived from ammonia (NH3) wherein hydrogen atoms are substituted by an aryl or alkyl group.