His M solution of histidine at a pH o

Organic Chemistry
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ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.SE: Something Extra
Problem 34AP: Using both three- and one-letter codes for amino acids, write the structures of all possible...
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The amino acid histidine has ionizable groups with pK, values of 1.8, 6.0, and 9.2, as shown.
COOH
CO
CO-
HN-CH
H,N-CH
H,N-CH
CH,
H,N-CH
CH, н
CH, H
CH2
1.8
6.0
9.2
CH
pk,
CH
pk,
CH
pK,
CH
H.
N.
N.
H.
lonizable -COOH
-COO-
-NH;
-HisH+ = -His
group
A biochemist makes up 80 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCI. What is the
pH of the resulting solution?
Transcribed Image Text:The amino acid histidine has ionizable groups with pK, values of 1.8, 6.0, and 9.2, as shown. COOH CO CO- HN-CH H,N-CH H,N-CH CH, H,N-CH CH, н CH, H CH2 1.8 6.0 9.2 CH pk, CH pk, CH pK, CH H. N. N. H. lonizable -COOH -COO- -NH; -HisH+ = -His group A biochemist makes up 80 mL of a 0.15 M solution of histidine at a pH of 5.3. She then adds 60 mL of 0.10 M HCI. What is the pH of the resulting solution?
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