H;N HO. Br (CH3CH2}3N quinapril racemic A

Q: carb (com unds synthesised large quantities in the chemical industry to be used as solvents and…

A: Oxidation of aldehyde group to carboxylic acid takes place when aldehyde reacts with CrO3 in water.…

Q: From what you have learned about enols and the hydration of alkynes, predict what product is formed…

A:

Q: The analgesic naproxen can be prepared by a stepwise reaction sequence from ester A. Using enolate…

A: The most acidic proton in compound A will be the one which is attached to the carbon adjacent to the…

Q: a) Define saponification. b) The following reactivity order has been found for the saponification of…

A:

Q: Farnesyl diphosphate is cyclized to sesquiterpene A, which is then converted to the bicyclic product…

A: The steps involved in the mechanism of the given reaction are as follows: The first step is the…

Q: Q1. Outline two methods of phenols synthesis. Q2. Give a concise account on the nomenclature of…

A:

Q: In the following scheme, establish who is A and B to obtain 2-tert-butyl-1-methyl-pyrrole C, write…

A: Reaction goes via friedel craft alkylation reaction.

Q: Which of the following will not provide an ether as a product? a. reduction of an alcohol b.…

A:

Q: Benzylamine synthesis from benzaldehyde follows the mechanism of reductive amination BECAUSE…

A: Statement 1: Benzylamine synthesis from benzaldehyde follows the mechanism of reductive amination…

Q: (a) p-Nitrobenzaldehyde is reactive toward nucleophilic additions than p- more methoxybenzaldehyde.…

A: a)

Q: Br CH,CO,H +Br, CH,CO,H CH3 `CH,CO,H CH3 A bromolactone

A:

Q: What product is formed when the esters in ginkgolide B, the chapter-opening molecule, are hydrolyzed…

A: The hydrolysis of esters in the presence of acid leads to the formation of carboxylic acids and…

Q: Identify compounds A, B, and C. a. Compound A has molecular formula C8H12 and reacts with two…

A: a) Since the degree of unsaturation for A = number of C + 1 - number of H / 2 = 8 + 1 - 12 / 2 = 3…

Q: Give the structure of compound A

A: The given reaction is a Friedel Crafts alkylation reaction. The reaction between arenes and acyl…

Q: Compound A of molecular formula C8H14 is reduced by sodium in liquid ammonia to give compound B of…

A:

Q: Aziridines are heterocycles that contain an N atom in a three-membered ring. Like epoxides,…

A: Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir…

Q: please help with this question. thank you.  The following sequence, beginning with a cyclic…

A: (1) Ring opening of A (Hemiocetal):

Q: The ketone shown was prepared in a three-step sequence from ethyl trifluoroacetate. The first step…

A: Ethyl Trifluoroacetate on reaction with NH3  give amide. Amides on reaction with Grignard reagent…

Q: 3. When the optically active compound shown below is treated with acid, the product is observed to…

A:

Q: Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting…

A:

Q: Acetylenic fatty acids are found in many tropical plants. Compound H, C13H2502, is one such…

A: Note : Compound H absorbs 5 equivalents of hydrogen. Therefore compound is have two triple bonds and…

Q: This question has multiple parts. Work all the parts to get the most points. The Stork reaction is a…

A:

Q: When a solution of (R)-2-methyl-1-phenyl butan-1-one in aq.EtOH is treated with either acid or base…

A: Given

Q: Identify compounds A, B, and C. a.) Compound A has molecular formula C8H12 and reacts with two…

A: a) Structure of HCOCH2CH2CHO   This compound is succinaldehyde. Reagents suggests that reaction…

Q: Compound A has molecular formula C7H15Br. Treatment of compound A with sodium ethoxide yields only…

A: given:  molecular formula of compound A =  C7H15Br. molecular formula of compound C = C7H16O.…

Q: Early organic chemists used the Hofmann elimination reaction as the last step of a process known as…

A: (a) If 2-methyl-3-pentanamine (A) undergoes methylation with methyl iodide and potassium carbonate…

Q: Compound A is an optically active alcohol. Treatment with chromic acid converts A intoa ketone, B.…

A: Chromic acid is an oxidising agent which converts alcohols to either aldehyde or ketone. Actually,…

Q: Rimantadine was among the first antiviral drugs to be licensed in the United States to use against…

A:

Q: D is an intermediate in the synthesis of rosiglitazone (trade name Avandia), a drug used to treat…

A: Body cells secrete many hormones which balance a person's metabolism. Hormones are basically…

Q: Choose the product that is expected when the β-pyranose form of compound A is treated with excess…

A:

Q: From each pair of compounds, choose the one with the indicated property and explain your choice. a)…

A:

Q: Selected organic compound: CARVACROL c) Illustrate a balanced chemical equation to synthesise…

A:

Q: D is an intermediate in the synthesis of rosiglitazone (trade name Avandia), a drug used for type 2…

A: The given compound D can be prepared by nucleophilic substitution of alcohol and alkyl halide in…

Q: Aziridines are heterocycles that contain an N atom in a three-membered ring. Like epoxides,…

A: Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir…

Q: Compound J, C16H16Br2, is optically active. On treatment with strong base, compounds K and L (each…

A: An optically active compound is one that shows optical rotation. It has been seen that pure chiral…

Q: From what you have learned about enols and the hydration of alkynes, predict what product is formed…

A: Note: In the question, double bond is shown instead of triple bond. Alkyne has triple bond

Q: Treatment of (HOCH2CH2CH2CH2)2CO with acid forms a product of molecular formula C9H16O2 and a…

A: The given compound in presence of an acid forms the product with molecular formula C9H16O2.

Q: Identify compounds A, B, and C. a.Compound A has molecular formula C8H12 and reacts with two…

A: Compound A – C8H12

Q: Lithiated pyrimidine is an important intermediate in the formation of the fungicide fenerimol. Give…

A:

Q: A step in a synthesis of PGE1 (prostanglandin E1, alprostadil) is reaction of a trisubstituted…

A: Bromination of alkene produce an bromonium ion intermediate. This bromonium formed stereoselective…

Q: The analgesic naproxen can be prepared by a stepwise reaction sequence from ester A. Using enolate…

A: The most acidic proton in compound A will be the one which is attached to the carbon adjacent to the…

Q: structure of N-ethyl-N-methycyclobutanamide i

A: The structure of a molecule gives the arrangement of atoms in space.

Q: Tranexamic acid, a drug useful against blood clotting, is prepared commercially from…

A: NBS (N-bromosuccinimide) is the most commonly used reagent to produce low concentrations of bromine.…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.