Hospital pharmacies and drug manufactures have various gelatin capsules that they can put drugs into, which will only dissolve in acidic or basic media, once they pass the mouth. This will be done to control where the drug will be introduced into the human digestive tract. We do not want things dissolving in the mouth or oral cavity. Additionally, most drugs will have several different functional groups in their structure, or we can consider them polyfunctional group molecules. With that said, please answer the following questions in order: a) Where will a capsule designed to dissolve in a basic environment dissolve, after it is swallowedwith a glass of water? b) What will happen (if anything) to a part of the drug molecule that is an amine salt, once the capsule dissolves? (Consider what will happen to it in the same location In the digestive tract where the capsule dissolves.) c) What will happen (if anything) to a part of the drug molecule that is a carboxylic acid, once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)

Hospital pharmacies and drug manufactures have various gelatin capsules that they can put drugs into, which will only dissolve in acidic or basic media, once they pass the mouth. This will be done to control where the drug will be introduced into the human digestive tract. We do not want things dissolving in the mouth or oral cavity. Additionally, most drugs will have several different functional groups in their structure, or we can consider them polyfunctional group molecules. With that said, please answer the following questions in order: a) Where will a capsule designed to dissolve in a basic environment dissolve, after it is swallowedwith a glass of water? b) What will happen (if anything) to a part of the drug molecule that is an amine salt, once the capsule dissolves? (Consider what will happen to it in the same location In the digestive tract where the capsule dissolves.) c) What will happen (if anything) to a part of the drug molecule that is a carboxylic acid, once the capsule dissolves? (Consider what will happen to it in the same location in the digestive tract where the capsule dissolves.)

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

See similar textbooks

Similar questions

The following molecules are lipids. Indicate to which lipid group each belongs.
Hair is made of protein. The protein is a structural protein called α-keratin, which contains many disulfide (S-S) bridges formed from sulfhydryl functional groups found amongst amino acids radical groups. Based on how the protein folds, the radical groups have opportunities to generate multiple disulfide bridges. The greater the number of disulfide bridges, the more tightly the hair is coiled. Using your knowledge of proteins, write a brief paragraph theocratizing how sodium hydroxide is used in hair products to straighten hair
Macromolecules are very large molecules created by the polymerization of small units called monomers. Most of the macromolecules are present in everyday life, for instance in food. In the Introduction to Food Macromolecules simulation, you will help your friend determine a healthy diet and investigate the types of macromolecules found in food. By performing a series of biochemistry tests, you will know the content of various food items. * * What are the different forms (i.e., monomers, polymers) of carbohydrates, lipids, and proteins? * What macromolecules do each of the biochemical tests check for? * What would an abundance or deficiency of one of the macromolecules cause to the human body?
Sphingolipids can contain of all of the following except A. glycerol. B. sphingosine. C. phosphocholine. D. a mono- or oligosaccharide.
Amino acids are the building blocks for proteins in the cell. The structures of the amino acids glutamate (or glutamic acid), glycine, and leucine are provided below in the same order from left to right. Map any chiral centers with a 1.
True or False: Beta sheets are helical structures please explain the answer, thanks
Which of the following is the best definition of a micromolecule
What is chemically nonsensical about this structure? H-C=C-H
When a substance such as sodium chloride is dissolved in water, the ions become completely surrounded by water molecules, forming structures called hydration spheres. When the sodium salt of a fatty acid is mixed with water, the carboxylate group of the molecule becomes hydrated, but the hydrophobic portion of the molecule is poorly hydrated, if at all. Using a circle to represent the carboxylate group and an attached squiggly line to represent the hydrocarbon chain of a fatty acid, draw a picture of how fatty acids interact with water.
Emergency treatment of cardiac arrest victims sometimes involves injection of a calcium chloride solution directly into the heart muscle. How many grams of CaCl2 are administered in an injection of 5.0 mL of a 5.0% 1m/v2 solution? How many milliequivalents of Ca2+?
Based on the structure below: 1. Based on the chemistry, is the drug phototoxic? (Yes or No) 2. Is the drug is acid-stable? (Yes or No) 3. Which of the following is TRUE about the structure shown? A. The drug is doxycycline. B. The drug is resistant against dehydration. C. The drug forms into a lactone when dehydrated. The drug is bactericidal. D. The drug is phototoxic.
Which of the following is true of sphingolipids? They always contain glycerol and fatty acids. They may be charged, but are never amphipathic. They contain two esterified fatty acids. Phosphatidylcholine is a typical sphingolipid. The sphingosine backbone is O-linked to a head group.