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- Figure 41.8 Loop diuretics are drugs sometimes used to treat hypertension. These drugs inhibit the reabsorption of Na+ and Cl- ions by the ascending limb of the loop of Henle. A side effect is that they increase urination. Why do you think this is the case?Diuretics cause sodium excretion. Sodium follows water. Therefore, diuretics lead to a reduction in volume (remember BP = heart rate x volume x blood vessel tone (SVR)). Since diuretics lower volume, they lower BP. When would diuretics be indicated? When would they be contraindicated?Studies have shown an increase in mortality when patients experiencing an acute episode of congestive heart failure are administered diuretics. Common loop diuretics include _____________ and _____________.
- A 65-year-old male patient is prescribed an ACE ( Angiotensin-converting enzyme) inhibitor (Benazepril ) for the treatment of hypertension. Which statement below is incorrect? Angiotensin II causes constriction of the vessels and triggers the release of aldosterone. ACE Inhibitors prevent Angiotensinogen I from converting to Angiotensin II. Kidneys will excrete water and potassium. This medication will lower SVR (systemic vascular resistance) and blood pressure.how does aldosterone raise blood pressure? Choose all that apply: distal convoluted tubule, collecting duct, increase sodium reabsorption, decrease sodium reabsorption, passive movement of water.How do diuretics work to reduce excess fluid in the body? Describe the mechanisms of action for three types of diuretics.
- Renin is released in response to ________.a. increased blood pressureb. decreased blood pressurec. ACEd. diureticsRenin Angiotensin Aldosterone System Decrease in blood flow (hypoxia) à decrease in oxygen in the kidney à kidney secretes 1. __________ à reaches the liver to secrete 2. _______________ à goes back to the blood stream. Blood brings it to the lungs which has 3. ________________ . The role of (#3) is to 4. ___________________________ à which is a potent vasoconstrictor if it binds to 5. ___________________ in blood vessels. This results to an increase in 6. ______________________ which will lead to an increase in 7. _____________________. Blood flow increases in the kidney, which will stop producing Renin. There is also an angiotensin 2 receptor in the 8. ____________________, where angiotensin 2 may also bind, leading to the production of 9. ______________________, which retains 10. _____________ and excretes potassium. Since sodium loves 11. _____________________, there is a further increase in 12. ________________ which further increases total peripheral resistance and blood…Which of the following is false about water reabsorption at the kidneys: a). Water is actively pumped from the tubules into the bloodb). A concentration gradient of sodium must be established to move Water c). The loops of Henie allow for water reabsorption d). Water moves through aquaporins
- Reabsorption of this chemical is a saturable process - inulin - bicarbonate - glucose - creatinine - calcium - adenosine - chloride - renin - aldosteroneIf a person has low blood pressure, what are some ways the body can compensate? A. Decrease ADH, Increase Aldosterone, Increase blood volume through activating thirst B. Increase in ADH, Increase in Aldosterone, Increase in thirst C. Decrease in ADH, Decrease in Aldosterone, Increase in thirst D. Increase ADH, Decrease Aldosterone, Decrease in thirst sensationWhich of the following are an effect of angiotensin II production? Select all that apply. Group of answer choices ADH release Rise in blood pressure Aldosterone release Vasodilation