How Mutations at the Huntington disease locusare caused?

Q: Why are chromosomal aberrations considered to have less significance than gene mutations for…

A: Chromosomal aberration refers to the alterations in a number of chromosomes such as loss or gain of…

Q: What causes the majority of the mutations found in human melanomas and lung cancer?

A: DNA is the chemical in each cells that makes up the genes and some genes control when cells grow,…

Q: What are the effects of Sxl mutations?

A: Mutations are defined as the change in the sequence of DNA of an organism due to any environmental…

Q: What are the chances of occurrence of neomorphic mutation?

A: Neomorphic mutations are rare dominant gain-of-function mutations that produce a novel phenotype.

Q: Why do gene mutations not result in chromosomal mutations?

A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…

Q: Is the mutation in the sickle cell gene a point mutation or a frameshift mutation?

A: Point mutations are a large category of mutations that describe a change in single nucleotide of…

Q: Can a child typically develop Huntington's Disease even if neither of the parents have the mutated…

A: Huntington's disease (HD) is an inherited disorder that causes nerve cells (called neurons) in parts…

Q: Why is fragile X, but not Huntington disease, considered a syndrome?

A: Fragile X syndrome causes various symptoms including developmental delays, cognitive impairment, and…

Q: What is the effect of inversion mutation?

A: Mutation is a change in the sequence of genetic material either due to the mistake in replication or…

Q: Explain the a gain-of-function mutation ?

A: Mutations occur when there is a change in DNA due to damage which can alter the gene expression.…

Q: Explain about the Identification and Cloning of the Huntington Gene ?

A: Genetics is a part of science worried about the investigation of genes, genetic variety, and…

Q: What causes Turner syndrome?

A: Sex Chromosome abnormalities causes turners syndrome. Persons with turners syndrome are…

Q: Which of the following are associated with dynamic mutations? O Genomic imprinting O Trinucleotide…

A: First of all we will discuss that, what is dynamic mutation and its causes.  Dynamic mutation is the…

Q: Why dominant negative mutation shows the haploinsufficiency  ?

A: A mutation is a change that occurs in our DNA sequence, either due to mistake when the DNA is copied…

Q: Explain down's syndrome?

A: The process of gamete formation involves meiotic division that results in cutting down the…

Q: How to identify all the somatic mutationswithin tumors ?

A: A somatic mutation is a modification within the desoxyribonucleic acid sequence of a somatic cell of…

Q: Explain Mutagenesis screens for maternal effect and zygotic lethal mutations?

A: The screen that is used in laboratory procedure to create or detect a mutant organism is called…

Q: What are mitochondrial mutations?

A: Mutations are defined as the change in the sequence of DNA of an organism due to any environmental…

Q: Which genetic disease is caused by the dysfunction of the 13th chromosome?

A: Chromosome 13 is one of the 23 sets of chromosomes in people. Individuals regularly have two…

Q: Which form of Retinoblastoma typically results in unilateral disease and exhibits 2-hit mutational…

A: Retinoblastoma is a cancer that affects the eyes. It is specifically a cancer of retinal layer of…

Q: What is the chromosome abnormality in cri du chat syndrome?

A: Cri-du-chat syndrome, commonly known as 5p- (5p minus) syndrome. Infants with this syndrome…

Q: Who was Mitochondrial Eve?

A: According to Abrahamic religion we come across theory of The Adam & The Eve who are 1st man…

Q: What is the phenotype associated with zygotic gene mutations?

A: ZYGOTE:- The male gamete "sperm" fuses with the female gamete "Ovum" and after this fusion "Zygote"…

Q: What is chromosome 15 abnormality?

A: Chromosomes are long thread-like structures that carry coded genetic information in the form of DNA.…

Q: What do you mean by holandric genes?

A: The genes residing exclusively on the Y chromosomes are known as holandric genes. These genes are…

Q: What is anomic aphasia?

A: The anomia is generally a language disorder - inability to express or communicate. It will slowly…

Q: What is the chromosome abnormality in fragile X syndrome?

A: Moderate mental retardation in affected individuals and mild cognitive impairment in affected…

Q: Besides CFTR, what othe gene is associated with cystic fibrosis?

A: Introduction Cystic fibrosis:- It is an inherited disorder that causes severe damage to the…

Q: What is the most important gene in the XIC?

A: XIC is the X- inactivation center present on the q (long) arm of X chromosome. This region includes…

Q: The maternal-effect mutation bicoid (bcd) is recessive. Inthe absence of the bicoid protein product,…

A: Introduction: Bicoid (Bcd) protein is a product of the bicoid gene having a maternal effect and is…

Q: What is the most common mitochondrial disease?

A: Mitochondria are cell organelles within eukaryotic cells, which produce adenosine triphosphate…

Q: What causes short stature in Turner syndrome?

A: Answer: Introduction: Turner syndrome (TS) is commonly found chromosomal disorders. It appears…

Q: What are chromosomal islands? Why are theyconsidered to be of foreign origin?

A: Chromosomes are long thread-like structures that carry coded genetic information in the form of DNA.…

Q: What is mitochondrial mutation?

A: Mitochondria are cell organelles present in aerobic eukaryotes that take part in oxidative…

Q: What are similarities between Jacob Syndrome and Patau Syndrome?

A: Jacob Syndrome is a chromosomal aberration caused by the non-disjunction of the Y chromosome. They…

Q: What is the significance of the Philadelphia chromosome, and how is it related to leukemia?

A: Chromosomes are the structures present in the nucleus that appear thread like and contain genes.…

Q: how this stuttering mechanism can change the number of repeat units at theSSR locus responsible for…

A: Huntington’s disease causes the progressive breakdown of nerve cells in the brain which causes the…

Q: Explain maternal-effect mutations?

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Q: Where is extrachromosomal DNA found?

A: Nucleic acids are the essential macro molecules that carry and transmit genetic information in the…

Q: The karyotypes shown here depict chromosomal abnormalities. Name the syndromes and if they are male…

A: "Genes" are the fundamental unit of heredity. They store genetic information in the form of DNA,…

Q: What is the Characteristic pedigree for mitochondrial disease?

A: The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human…

Q: What are three similarities and three differences between Germline mutations and Somatic mutations?

A: A mutation refers to the alteration in the sequence of DNA (deoxyribonucleic acid). It can be a…

Q: Does The Effects of a Mutation Can Be Difficult to Predict?

A: A mutation is a change that occurs in the deoxyribonucleic acid (DNA) when it is damaged or changed…

Q: Compare and contrast the molecular mechanisms leading to FX syndrome and to FSHMD.

A: Introduction :- A gene originally known as FMR1 gene by scientists and responsible for FXS is…

Q: What is retrograde?

A: Introduction  The proteins which are formed by the ribosomes attached over the ER are transported to…

Q: What is mutation? Distinguish between (i) neutral and silent mutation (ii) germ line and somatic…

A: Mutations can sometimes be beneficial, when they result in traits that will benefit the organism.…

Stress

Stress is defined as the feeling of being overwhelmed or unable to cope with emotional or mental pressure. Any event or action that makes a person annoyed, furious, or nervous can trigger it. Chemical changes in the body caused by stress can cause blood pressure, blood sugar levels, and heart rate to rise.