How would you use a silyl enol ether to make this aldol product? Why is it necessary to use this particular intermediate? What would be the products be if the two carbonyl compounds were mixed and treated with base? + CHO CHO CHO

Q: H;C CH3 -CH=CH-C -CH,CH3 -CH=Ċ- -CH3

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Q: Draw the product formed (after dehydration) in the crossed aldol condensation of phenylacetaldehyde…

A: Cross aldol reaction is the reaction between two different aldehyde or ketone compounds. The product…

Q: Propose a mechanism for the aldol condensation of cyclohexanone. Do you expect theequilibrium to…

A: In base-catalyzed aldol condensation, nucleophilic addition of an enolate ion takes place on a…

Q: Describe how the following compound can be prepared using an aldol addition in the first step of the…

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Q: Describe how the following compound can be prepared using an aldol addition in the first step of the…

A: An aldol reaction is a reaction in which an enol or an enolate ion reacts with a carbonyl compound…

Q: What product results when an aldol product is dehydrated? A) conjugated alkyne B) B-diketone C)…

A: Dehydration is a process in which H2O is leave

Q: 4. Give the structures of two compounds that can react together to form the following compound by a…

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Q: ...

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Q: 4. Give the crossed aldol product for the following reaction. NaOH (aq) + H. 25 °C

A: The Cross Aldol condensation reaction is a type of organic reaction . In the Reaction two Carbonyl…

Q: Describe how the following compounds can be prepared using an aldol addition in the first step of…

A: First step in the preparation is the abstraction of proton from the carbonyl compound by a base…

Q: 4. Give the structures of the aldol products that form when each of the following compounds or…

A: Hey, since there are subpart questions posted, we will answer three subparts. If you want any…

Q: Draw the step-by-step mechanisms for the following reactions: a) Step 1 of the aldol condensation OH…

A: Aldol condensation reaction can be defined as the chemical reaction of an enolate ion with the given…

Q: *Pu OK it 90 °C

A: An aldol condensation is a condensation reaction in which an enolate ion reacts with a carbonyl…

Q: Consider the mechanism for the aldol condensation shown below. Which of the following statements…

A: Applying concept of acid catalysed  aldol reaction.

Q: Propose a mechanism, using curved arrows, for the base-catalysed aldol reaction and the subsequent…

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Q: In theory, the intramolecular aldol reaction of 6-oxoheptanal could yield the three compounds shown.…

A: The mechanism of the given reaction involving the formation of (I) compound is shown as,

Q: Describe how the following compound can be prepared using an aldol addition in the first step of the…

A: Aldol addition is the nucleophilic addition reaction which takes place when the enolate of the…

Q: The product below can be synthesized by a Robinson annulation, which is a Michael addition followed…

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Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: The reaction taking place is given as,

Q: Write the structure for each aldol condensation product that is possible when a mixture of ethanal…

A: In aldol condensation, first enolate will generate. Here ethanal and propanal both can form enolate…

Q: Draw the product formed when each dicarbonyl compound undergoes an intramolecular aldol reaction…

A: Given compounds,

Q: 17. Which of the following are intermediates in the acid catalyzed aldol reaction of propanal to…

A: Aldol reaction can occur in both basis and acidic medium

Q: (A) OC H3 (B) (c) CH3

A: The aldol condensation reaction is given below

Q: What is TRUE about the reaction below? Select one: O a. The reaction has the same rate when the base…

A: Organic reactions are those in which organic reactant react to form organic products.

Q: There are other condensation reactions similar to the aldol and Claisen condensations: a. The Perkin…

A: The Perkin condensation is the condensation of an aromatic aldehyde and acetic anhydride. It is…

Q: There are other condensation reactions similar to the aldol and Claisen condensations:a. The Perkin…

A: Aromatic aldehydes when heated with the anhydride of an aliphatic acid(containing two alpha…

Q: How would you prepare the following compounds using aldol condensation reaction?

A: The given compound is known as methyl vinyl ketone. This can be synthesised by the Aldol…

Q: Write the structures of the enone products you would obtain from aldol conden- sation of the…

A: Given compounds are : Write the structures of the enone products you would obtain from condensation…

Q: What is the first step in the acid-catalyzed aldol condensation reaction. Attack of the…

A: Hi, we are supposed to answer one question. To get the remaining questions solved please mention the…

Q: In theory, the intramolecular aldol reaction of 6-oxoheptanal could yield the three compounds shown.…

A: Step:1 6-Oxoheptanal gives 1-acetyl cyclopentene.

Q: Describe how the following compound can be prepared using an aldol addition in the first step of the…

A: Acetaldehyde is reacted with a strong base, LDA to form resonance-stabilized enolate ion.

Q: Give the aldol product and step wise reaction mechanism for the following reaction: NaOH CH;CH;OH

A: Using aldol reaction concept followed by E1cb elimination reaction.

Q: NaOH + 2 H, Explain why more than two equivalents of the aldehyde was needed in order to optimize…

A: Mixed aldol reactions involve two different carbonyl compounds. Up to four products are possible…

Q: In the following aldol condensation reaction, two different carbonyl compounds were used, and only…

A: It is an aldol condensation of ketone with another aldehyde in presence of a base such as NaOH.

Q: What is the product if this compound underwent aldol condesation with a base (NaOH), and how?

A: Answer

Q: What product would you expect to obtain from aldol cyclization of hexanedial, OHCCH2CH2CH2CH2CHO?

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Q: CH, KOH CH二CH NO2

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Q: What aldol product is formed when two molecules of butanal react together in the presence of base?…

A: Aldol condensation takes place in only those aldehyde and ketone compounds which possess atleast one…

Q: tu II it 1ONIlal 1epot. OH ОН О H. A For the "crossed" aldol reaction that lead to product C, did…

A: Aldol condensation is a very important reaction in organic chemistry. This is a condensation between…

Q: Which of the following compounds would you expect to undergo aldol self- condensation? Show the…

A: A condensation reaction is that in which two mole of the same molecule are condensed.

Q: Aldol product Donor Acceptor сно OH 2. но co,C2H5 CHO CHO A B D co,C2H5 F CHO co,C2HS

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Q: Identify the major aldol condensation product obtained when the following compound is heated in the…

A: Given compound is pentanal  And it has aldehyde functionality. It is a base catalyst reaction.…

Q: For the following reaction: H NaOH CH3CH₂OH a Draw the major organic product, assuming no…

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Q: What carbonyl starting materials are needed to prepare each compound using a directed aldol…

A: For aldol reaction, aldehyde and ketones must have atleast one alpha hydrogen atom when treated with…

Q: Show how to prepare   a,b-unsaturated aldehyde by an aldol reaction followed by dehydration of the…

A: Aldol reaction is a fine method to introduce a carbon-carbon bond and increase the number of carbon…

Q: What reactant can be used to make this compound by an intramolecular aldol reaction? (A) (B) (C) (D)…

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Q: b. ) What starting compound would you use in an Aldol condensation in the following compound?…

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Q: Draw the aldol product for the reaction of the aldehyde shown with NaOH. Assume the reaction is run…

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Q: 4.Which is the most thermodynamically stable product of the following aldol condensation reaction?…

A: I would Say E,E  as Phenyl Group is bulky so it will prefer to go on E- configuration

Q: What aldol product is formed when two molecules of butanal react together in the presence of base?…

A: What aldol product is formed when two molecules of butanal react together in the presence of base?…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.