Ibuprofen is a drug used to manage mild pain, fever, and inflammation. It is a chiral drug, and only the S enantiomer, whose specific rotation is +25.0°, is effective. The R enantiomer exhibits no biological activity. If a particular process is capable of producing ibuprofen in 84% enantiomeric excess of the S enantiomer, then what is the specific rotation of that mixture? What is the percentage S enantiomer in that mixture?

Ibuprofen is a drug used to manage mild pain, fever, and inflammation. It is a chiral drug, and only the S enantiomer, whose specific rotation is +25.0°, is effective. The R enantiomer exhibits no biological activity. If a particular process is capable of producing ibuprofen in 84% enantiomeric excess of the S enantiomer, then what is the specific rotation of that mixture? What is the percentage S enantiomer in that mixture?

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter5: Stereochemistry At Tetrahedral Centers

Section5.SE: Something Extra

Problem 54AP

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