If you were to mutate Ser195 in the catalytic triad of chymotrypsin to another amino acid, which amino acid change would you expect to have the least effect on chymotrypsin catalytic activity? O Ala Val Phe Thr O Leu

If you were to mutate Ser195 in the catalytic triad of chymotrypsin to another amino acid, which amino acid change would you expect to have the least effect on chymotrypsin catalytic activity? O Ala Val Phe Thr O Leu

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 14QP: If phenylalanine was not an essential amino acid, would diet therapy (the elimination of...

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Concept explainers

Nitrogen metabolism

Nitrogen metabolism is the synthesis, utilization or uptake, breakdown, and excretion of nitrogenous compounds in the body. The nitrogen metabolism encompasses nitrogen fixation, biosynthesis, and the breakdown of amino acids, purines, and pyrimidine. Since nitrogen-containing compounds are required for various life processes, nitrogen is an important element of life.

Question

If you were to mutate Ser195 in the catalytic triad of chymotrypsin to another amino acid, which
amino acid change would you expect to have the least effect on chymotrypsin catalytic activity?
O Ala
O Val
O Phe
O Thr
O Leu

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