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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 10, Problem 14QP
Textbook Problem
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If phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work?

Summary Introduction

To explain: Whether diet therapy would have worked for PKU if phenylalanine was not an essential amino acid.

Introduction: Phenylalanine is an essential amino acid which is a precursor for tyrosine. Phenylalanine is also a precursor for many other compounds that act as neurotransmitters in the body. It is metabolized to tyrosine by the enzyme phenylalanine hydroxylase. In people who are suffering from phenylketonuria disease, a malfunctioned enzyme is produced due to some genetic changes, which leads to an accumulation of phenylalanine in the body.

Explanation of Solution

In normal individuals, phenylalanine is an essential amino acid that is obtained through dietary mode. So, in a person suffering from phenylketonuria, the dietary restrictions can prevent the harmful effects caused by the accumulation of phenylalanine in the body...

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