Imagine that you could microinject cytochrome cinto the cytosol of wild-type mammalian cells and of cellsthat were doubly defective for Bax and Bak. Would youexpect one, both, or neither type of cell to undergo apopto-sis? Explain your reasoning.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter17: Metabolism: An Overview
Section: Chapter Questions
Problem 9P
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Imagine that you could microinject cytochrome c
into the cytosol of wild-type mammalian cells and of cells
that were doubly defective for Bax and Bak. Would you
expect one, both, or neither type of cell to undergo apopto-
sis? Explain your reasoning.

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