In a study by Marsaioli et al. the tranport of the antibiotic fosfomycin was shown to be facilitated by a an active proteic transport system, rather than via passive diffusion through the phospohlipidic membranes. The did this by employing STD-NMR, which showed a prefered interaction between specific parts of the fosfomycin molecule (otherwise known as an epitope) and Human serum albumin (HSA). H Hạc H3C PO3NA2 fosfomycin The below spectra are the A off- resonance (set at 30ppm) and B the on-resonance spectrum (set at -0.5ppm). The signal at 3.2ppm is a multiplet. The signal at 2.7ppm is a doublet of doublets and signal at 1.4ppm is a poorly resolved doublet. Th 3 S.5 5.0 4.5 4.0 3.5 3.D 2.5 2.0 1.5 1.0 0.5 Ppm

In a study by Marsaioli et al. the tranport of the antibiotic fosfomycin was shown to be facilitated by a an active proteic transport system, rather than via passive diffusion through the phospohlipidic membranes. The did this by employing STD-NMR, which showed a prefered interaction between specific parts of the fosfomycin molecule (otherwise known as an epitope) and Human serum albumin (HSA). H Hạc H3C PO3NA2 fosfomycin The below spectra are the A off- resonance (set at 30ppm) and B the on-resonance spectrum (set at -0.5ppm). The signal at 3.2ppm is a multiplet. The signal at 2.7ppm is a doublet of doublets and signal at 1.4ppm is a poorly resolved doublet. Th 3 S.5 5.0 4.5 4.0 3.5 3.D 2.5 2.0 1.5 1.0 0.5 Ppm

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter31: Immunochemistry

Section: Chapter Questions

Problem 31.69P

See similar textbooks

Similar questions

1.Which of the following correlations about the analyses of iodine and saponificationnumbers is/are incorrect?a. Alcoholic KOH: dissolve KOH to lipid sampleb. Hanus reagent: react with saturated lipid bondc. Reflux set-up: hasten reactiond. Blank titration: determine total mol of KOH2. A triacylglycerol (Sample X) was subjected to saponification analysis. 1.1 grams of thesample was refluxed with 5% alcoholic KOH and the refluxed solution was titrated with 17.2 mLof 0.44 M HCl titrant. The blank solution was titrated with 25.6 mL of the titrant.i. What is the saponification number of the sample? ii. Which of the following could be the identity of the sample? Show solutions pls a. Tripalmitin (MW: 807.3)b. Trilaurin (MW: 639.8)c. Triolein (MW: 885:4)d. Tristearin (MW: 891.48)
A nickel-containing transmembrane protein ___________. Select one: a. contains a cofactor and is found in the cytosol b. contains a cofactor and is found in the cell membrane c. is a dimer and is found in the cytosol d. contains a cofactor and is a dimer e. is a dimer and is found in the cell membrane
if possible please post links used for summary a. Summarize and briefly explain the chemical interaction between EDC and NHS in Electrochemical Biosensing (CHEMICAL NAME: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide/N-hydroxysuccinimide) b. Summarize and briefly explain the chemical interaction between Biotin & Avidin in Electrochemical Biosensing
Below are responses generated using the isolated guinea-pig ileum preparation to determine a pA2 value for the cholinergic antagonist homatropine.Responses are expressed in millimetres +/- SDM (n = 4).Plot the data and then determine by Schild analysis the pA2 value and Schild slope. show calculationsWhat conclusions can you draw; does the experiment/data fulfil the criteria for a valid Schild analysis?
Drugs called COX-2 inhibitors (e.g., Vioxx, Bextra, andCelebrex) were thought to relieve the pain and inflammation ofosteoarthritis without the stomach bleeding and ulcers non-steroidal anti-inflammatory drugs (NSAIDs) cause. In a 12-month trial, Vioxx caused fewer gastrointestinal side effectsthan the NSAID ibuprofen. However, a study of the recurrenceof colon polyps after three years of Vioxx found an increasedrisk for heart attack and stroke beginning after 18 months oftreatment. As a result, Vioxx was withdrawn from the market,and an FDA panel concluded that COX-2 inhibitors as a classhave increased cardiovascular risk that varies by drug anddose. The FDA then caused the withdrawal of Bextra and re-quired a warning label on Celebrex. Based on this information,list (a) an observation, (b) a hypothesis, (c) an experiment, and(d) a theory.
The data below give the concentration of thiol (mM) in the blood lysate of the blood of two groupsof volunteers, the first group being ‘normal’ and the second having rheumatoid arthritis (Banford, J.C.,Brown, D.H., McConnell, A.A., McNeil, C.J., Smith, W.E., Hazelton, R.A. and Sturrock, R.D., 1983,Analyst, 107: 195): Normal: 1.84, 1.92, 1.94, 1.92, 1.85, 1.91, 2.07Rheumatoid: 2.81, 4.06, 3.62, 3.27, 3.27, 3.76 Verify that 2.07 is not an outlier for the ‘normal’ group.
ondition wherein there is cholesterol deposition in the lamina propria of gallbladder
5 optimise, produce and market a commercial assay kit for the enzyme-linked determination of glucose in a range of samples
1. A mixture of proteins (pepsinogen, myoglobin, and cytochrome c) is subjected to anion exchange chromatography at pH 5.0. In what order would the following proteins be eluted from the DEAE cellulose anion exchanger by an increasing salt gradient: cytochrome c (pl, 10.6), pepsinogen (pl, 1.0) and myoglobin (pl, 6.8)
One of the drawbacks of older methodology for nonprotein testing was that ________________, which modern methods have corrected for. Question 2 options: A) a protein-free filtrate needed to be made B) it was difficult to separate BUN from creatinine C) ammonia was too volatile D) substrate was a limiting factor
Below are responses generated using the isolated guinea-pig ileum preparation to determine a pA2 value for the cholinergic antagonist homatropine.Responses are expressed in millimetres +/- SDM (n = 4).Plot two data graph and then determine by Schild analysis the pA2 value and Schild slope. show calculationsWhat conclusions can you draw; does the experiment/data fulfil the criteria for a valid Schild analysis?
Below are responses generated using the isolated guinea-pig ileum preparation to determine a pA2 value for the cholinergic antagonist homatropine.Responses are expressed in millimetres +/- SDM (n = 4).1. Plot the data on excel and then determine by Schild analysis the pA2 value and Schild slope 2. show all calculation on a sheet of paper 3. discuss the result with conclusion