In Drosophila, the autosomal recessive dp allele ofthe dumpy gene produces short, curved wings, whilethe autosomal recessive allele bw of the brown genecauses brown eyes. In a testcross using femalesheterozygous for both of these genes, the followingresults were obtained:wild-type wings, wild-type eyes 178wild-type wings, brown eyes 185dumpy wings, wild-type eyes 172dumpy wings, brown eyes 181In a testcross using males heterozygous for both ofthese genes, a different set of results was obtained:wild-type wings, wild-type eyes 247dumpy wings, brown eyes 242a. What can you conclude from the first testcross?b. What can you conclude from the second testcross?c. How can you reconcile the data shown in parts (a)and (b)? Can you exploit the difference betweenthese two sets of data to devise a general test forsynteny in Drosophila?d. The genetic distance between dumpy and brown is91.5 m.u. How could this value be measured?
In Drosophila, the autosomal recessive dp allele of
the dumpy gene produces short, curved wings, while
the autosomal recessive allele bw of the brown gene
causes brown eyes. In a testcross using females
heterozygous for both of these genes, the following
results were obtained:
wild-type wings, wild-type eyes 178
wild-type wings, brown eyes 185
dumpy wings, wild-type eyes 172
dumpy wings, brown eyes 181
In a testcross using males heterozygous for both of
these genes, a different set of results was obtained:
wild-type wings, wild-type eyes 247
dumpy wings, brown eyes 242
a. What can you conclude from the first testcross?
b. What can you conclude from the second testcross?
c. How can you reconcile the data shown in parts (a)
and (b)? Can you exploit the difference between
these two sets of data to devise a general test for
synteny in Drosophila?
d. The genetic distance between dumpy and brown is
91.5 m.u. How could this value be measured?
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