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In each cell if DNA polymerase I is non-functional, how would it affect the leading strand
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- What does DNA polymerase III need to catalyze DNA synthesisWhat is meant by non-classical DNA-dependent DNA polymerases? What roles do they play in our cells?The topoisomerase enzyme catalyzes the interconversion of the relaxed and supercoiled forms of DNA by making transient breaks in one or both DNA strands. What is the difference between I and II?
- In one, simple sentence define the function of the following 1. Helicase = 2. Alpha subunit of DNA polymerase III =besides DNA pol I and DNA pol III What are the roles of the other enzymes involved in replication and why they're necessary ?1.1 What components must be available for DNA polymerase III to proceed with DNA synthesis during replication? 1.2 What will the consequences for the cell be if the following enzymes are not functioning? DNA polymerase III Primase DNA ligase
- Why would replication come to a halt in the absence of topoisomerase II?If a prokaryotic cell experienced a mutation that eliminated DNA polymerase's 3' to 5' exonuclease activity, what part of DNA synthesis would be affected?During high stress environments, it has been found that some bacteria activate a genetic mechanism that allows them to incorporate more mutations into the DNA during replication. Would the following two enzymes be impacted by such a mechanism? (i)DNA polymerase IIIii) Helicase
- What is The molecular mechanisms governing the initia-tion of DNA replication.If a eukaryotic chromosome has 25 origins of replication, how many replication forks does it have at the beginning of DNA replication?The epsilon subunit of DNA polymerase III is responsible for its _______ activity.A-5'---->3' polymerase B- Sliding clampC-3'----->5' exonuclease activity D-5'------>3' exonuclease activity