In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?   The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual. None of the other answers are correct. The AY allele lacks an upstream merc gene which is required for normal embryonic development. The AY allele contains a null mutation in the A gene, which is required for normal embryonic development. The yellow pigment produced by A allele is required for survival.

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
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Chapter19: Introduction To Genetics
Section: Chapter Questions
Problem 9CT
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In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?
 
The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual.
None of the other answers are correct.
The AY allele lacks an upstream merc gene which is required for normal embryonic development.
The AY allele contains a null mutation in the A gene, which is required for normal embryonic development.
The yellow pigment produced by A allele is required for survival.
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