A standard three-point mapping is conducted for recessive mutations in autosomal genes purple eye (pr), curved wing ( c) and black body (b). Their wild type alleles are also used for genetic mapping. An F1 Drosophila female heterozygous for purple eye (pr), curved wing (c) and black (b) is crossed to a triply homozygous mutant male. The observed numbers and phenotypes of the offspring are as follows: 360 pr c b

Human Biology (MindTap Course List)
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Author:Cecie Starr, Beverly McMillan
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Chapter20: Chromosomes And Human Genetics
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Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....
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A standard three-point mapping is conducted for recessive mutations in autosomal genes purple eye (pr), curved wing ( c) and black body (b). Their wild type alleles are also used for genetic mapping. An F1 Drosophila female heterozygous for purple eye (pr), curved wing (c) and black (b) is crossed to a triply homozygous mutant male. The observed numbers and phenotypes of the offspring are as follows:

360 pr c b

380 pr+ c+ b+

104 pr c+ b

96 pr+ c b+

30 pr c b+

20 pr+ c+ b

6 pr c+ b+

4 pr+ c b

PROVIDE THE FOLLOWING:

A) State the order of genes on this chromosome.

B) Calculate map distances between the gene pairs: pr-c, pr-b, c-b. Show calculations, state the number of map units and which gene pairs they refer to.

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